Scientific Officer – Liquid Biopsy Research

Overview

Fixed term until 31st March 2028.

The goal of the CRUK National Biomarker Centre (NBC) is to develop, validate, and implement biomarkers that facilitate the optimisation of cancer patient treatment. The NBC is a world leader in the study of minimally invasive biomarkers, or liquid biopsies, and integrates clinical, experimental and computational science into a convergent programme. Translational research and clinical implementation are central to this biomarker agenda.

An exciting opportunity has arisen for a Scientific Officer to join the Nucleic Acids Biomarker (NAB) team of the NBC. You will work alongside a multidisciplinary team of biologists, clinicians, engineers, and computational scientists. The NAB team is developing new molecular assays from liquid biopsy samples.

Working closely with experienced staff, the appointee will be aligned to the processing, banking and analysis of important clinical trial samples to monitor and evaluate clinical studies and will be required to work under Good Clinical Practice (GCP) regulations. Biomarkers analysed may include circulating cell-free DNA and other liquid biomarkers. All the required training and supervision will be provided.

• Align with the processing, banking and analysis of important clinical trial samples to monitor and evaluate clinical studies.
• Work under Good Clinical Practice (GCP) regulations.
• Assist in developing molecular assays from liquid biopsy samples.
• Collaborate with a multidisciplinary team including biologists, clinicians, engineers and computational scientists.
• Participate in training and supervision as provided.

• A degree in molecular biology or a relevant scientific discipline (or equivalent relevant experience) with laboratory experience.
• Desirable: keen interest in cancer biology, willingness to learn new skills and contribute to cancer research.
• Desirable: experience handling clinical samples, ideally in a cancer research setting.
• Effective communication, good organizational skills and basic computer skills are essential.
• Previous experience working in a Good Laboratory Practice (GLP/GCP) environment would be advantageous.

The Cancer Research UK Manchester Institute is a world-leading centre for cancer research, core funded by Cancer Research UK. We are partnered with The Christie NHS Foundation Trust in South Manchester, one of the largest cancer treatment centres in Europe, providing an environment to pursue basic, translational, and clinical research programmes.

The Cancer Research UK National Biomarker Centre sits at the convergence between discovery science and translational research and aims to develop the next generation of cancer biomarkers.

To apply for this position please visit our website:

For informal enquiries about this post, please contact Dr Florent Mouliere via email: florent.mo

The deadline for receipt of applications is: 11th February 2026