Senior Clinical Research Nurse

Job Summary

The post of Senior Clinical Research Nurse for CAR-T cell trials (Haematology and Lymphoma) presents an exciting opportunity to join two established and successful research teams with a varied and expanding portfolio of CAR-T cell clinical trials. The teams also support a large number of industry-led, non-commercial and academic-led trials, ranging from early to late-phase studies. We are seeking an enthusiastic and highly motivated individual who will be responsible for the management and coordination of CAR-T cell clinical research studies, from set-up through to archiving, within haematology and lymphoma.

This is a newly developing role within an established group of clinical research nurses.

The post holder will work collaboratively with Consultants, Clinical Fellows, Research Nurses, Clinical Trial Pharmacists and Cell Laboratory staff, Clinical Trial Coordinators and other supporting service departments involved in CAR-T cell therapy. In addition, the role includes line management responsibilities and participation in the senior research teams within haematology and lymphoma research.

Key responsibilities include the management and coordination of CAR-T cell clinical trials in haematology and lymphoma, ensuring that research is conducted in accordance with the requirements of a multi-regulated clinical research environment and that patient safety and wellbeing are safeguarded. The role also includes leadership and management responsibilities, supporting the Clinical Research Matron. You will interact with a wide range of research professionals, haematology and lymphoma specialists and staff across The Christie, as well as commercial partners, other NHS institutions, research bodies and the wider community.

A proactive approach to professional development is essential, alongside the ability to demonstrate expertise in CAR-T cell therapy, initiative for team development and training programmes. By utilising national frameworks to audit patient experience, you will ensure that participants in CAR-T cell portfolio studies receive the best possible experience while taking part in clinical research. Further responsibilities include raising the profile of the clinical research nurse role and CAR-T cell clinical trials both within the Trust and externally, engaging in promotional events related to clinical research and contributing to divisional, Trust-wide and national objectives and strategies.

The Christie is one of Europe s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world;

chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

Date posted: 14 January 2026
Pay scheme:
Agenda for change
Band:
Band 7
Salary: £47,810 to £54,710 a year Per annum, Pro rata

Contract:

Permanent
Working pattern:
Full-time
Reference number: RI-DA
Job locations:
Haematology - Q00675, Manchester, M20 4BX

Duties and Responsibilities

• Clinical Research Co-ordination:
  Work autonomously in all areas of practice relating to clinical research. Understand and deliver care in accordance with regulatory approved clinical research protocols. Oversee the process for obtaining NHS permissions (R&D approval) for clinical trials within team. As project lead, ensure permissions are in place prior to any patient recruitment. Undertake feasibility and risk assessments of clinical trial protocols in conjunction with Team Leader, Principal…