Senior Clinical Research Fellow; Christie-Peter Mac

A unique opportunity to undertake a 2-year clinical fellowship based between two world leading Phase I units, year 1 spent at The Christie NHS Foundation Trust Manchester, UK, year 2 moving to The Peter Mac Callum Cancer Centre Melbourne, Australia. We are seeking ambitious & innovative individual with an interest in early phase clinical trials & research.

With consultant oversight you will be responsible for seeing new referrals, follow-ups & managing patients throughout all aspects of their trial experience. There is opportunity to undertake a postgraduate MD degree fully funded and co-supervised by colleagues at The Christie & Peter Mac via The University of Manchester.

The position is suitable for those on a specialist oncology training pathway preference will be given to those who are towards the end or having completed this, and who wish to gain further experience in experimental medicine & Phase I trials, including first-in-human trials, clinical pharmacology trials & translational research.

Salary will be on The Christie and Peter Mac scales in line with appropriate clinical experience. Candidates are encouraged to discuss the renumeration package ahead of application. We anticipate the fellowship commencing in Manchester between Summer 2026 & February 2027, with some flexibility.

Please note interviews are likely to be outside of normal UK working hours to facilitate a joint interview panel between The Christie and PMCC.

The portfolio includes a diverse range of clinical research trials. Following training, you will be expected to participate in these studies as a sub-investigator. These may include phase I trials of small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality phase I trials, advanced therapy trials, molecular characterisation / translational studies, radiotherapy trials.

You will be involved in managing all aspects of trial patients (both in outpatient & in-patients setting), across a diverse range of solid tumours, through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments.

You will be expected to attend safety review committee meetings to discuss trial patients. This will involve close liaison with the Principal Investigators. In addition, you will interface with external stakeholders such as CROs & pharmaceutical sponsors.

You will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enrol in early phase trials.

You will be expected to undertake the administrative duties associated with the care of our patients. You will be given opportunities and will be encouraged to be involved in the development & planning of new studies.

There is potential to present your research work and you will be expected to be involved in writing papers and reviews. You will also be required to undergo an annual appraisal.

The Christie is one of Europe's leading cancer centres, treating over 64,000 patients a year. We are based in Manchester and serve a population of 3.2 million. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services.

We are an international leader in research and run one of the largest early clinical trial units in Europe with over 300 trials every year.

The Peter Mac Callum Cancer Centre is Australia's only public comprehensive cancer centre exclusively dedicated to cancer care. Located in Melbourne, Peter Mac is a global leader in cancer research, education, and treatment. Peter Mac is home to the largest grouping of cancer researchers in Australia, who work alongside specialist teams to deliver exceptional care and drive groundbreaking research. Peter Mac is recognised for its extensive clinical trial capabilities, supported by the Parkville Cancer Clinical Trials Unit (PCCTU), Australia's largest cancer trials unit, which specialises in first-in-human trials.

Peter Mac's Early Drug Development (EDD) program plays a key role in advancing new therapies from discovery to patient care. Note, that the full job description and role for the second year of the fellowship will be provided and facilitated through The Peter Mac Callum Cancer Centre.

The medical establishment based at The Christie provides 5 Consultant Medical Oncologists, and 3+ Senior/Clinical Fellows within the ECM team. The medical establishment based at Peter Mac Cullum is integrated into the Department of Medical Oncology; with 7-8 of these Consultant Medical Oncologists acting as Principal Investigators in the Early Drug Development Program, along with 4 Early Drug Development Fellows integrated with the team.

Continuing Professional Development The Trust supports the…