Cloud & Linux System Engineer III

Join to apply for the Cloud & Linux System Engineer III role at Biodesix, Inc.

Referrals increase your chances of interviewing at Biodesix, Inc. by 2x.

Biodesix is a leading diagnostic solutions company, driven to improve clinical care and outcomes for patients. Biodesix Diagnostic Tests support clinical decisions to expedite personalized care and improve outcomes for patients with lung disease. Biodesix Development Services enable the world’s leading biopharmaceutical, life sciences, and research institutions with scientific, technological, and operational capabilities that fuel the development of diagnostic tests, tools, and therapeutics.

Our Mission
:
Transform patient care and improve outcomes through personalized diagnostics that are timely, accessible, and address immediate clinical needs.

Our Vision
: A world where patient diseases are conquered with the guidance of personalized diagnostics.

For more information, please visit

The Cloud & Linux System Engineer III serves as the primary owner responsible for engineering, securing, and continuously improving Biodesix’s cloud platforms and Linux-based systems in support of regulated healthcare diagnostics. This role ensures stability, performance, and security of production environments while enabling the deployment of new applications, data services, and infrastructure capabilities that directly support our clinical and commercial operations.

This role sets standards for cloud and Linux engineering practices and serves as a subject matter expert for regulated infrastructure environments. This position collaborates closely with security, software development, data engineering, and laboratory operations teams to maintain compliant, scalable, and highly available cloud environments.

On‑Site in Louisville, CO

• Act as a subject matter expert for AWS workloads supporting CLIA/CAP/ISO‑controlled laboratory systems.
• Design, implement, and manage scalable, secure cloud environments using AWS services (EC2, S3, RDS, VPC, IAM, Cloud Watch, etc.).
• Optimize AWS infrastructure for performance, reliability, and cost efficiency.
• Implement and maintain IAM roles, policies, VPC architecture, and network security controls.
• Manage cloud‑based backup, DR policies, and recovery procedures.
• Maintain audit readiness for system configurations, access controls, and change records.

• Install, configure, secure, and maintain Linux‑based servers and associated services.
• Perform system updates, patches, kernel updates, and vulnerability remediation.
• Monitor performance, troubleshoot system issues, and tune resource utilization.
• Support and manage services and architectures including Apache, MySQL/Postgres, Docker, and related components.
• Automate recurring tasks using shell scripting and/or configuration management tools.

• Lead complex troubleshooting and root‑cause investigations with cross‑functional partners.
• Define and maintain infrastructure patterns, implementation standards, and automation frameworks.
• Identify system risks proactively and drive remediation plans to closure.
• Contribute to infrastructure roadmap direction and technology adoption strategy.
• Partner with development and Dev Ops teams to support CI/CD pipelines and deployment workflows.
• Maintain structured documentation for configurations, procedures, standards, and infrastructure changes.
• Participate in incident response, root cause analysis, and after‑action reporting.
• Provide Tier 3 support and escalate critical issues as required.
• Support ticketing, ITIL‑aligned change processes, and on‑call rotation for production systems.
• Contribute to departmental goals, continuous improvement, and IT modernization initiatives.
• Mentor junior and mid‑level engineers, enabling skill development in cloud and Linux engineering practices.

• Associate’s or Bachelor’s degree in Information Systems, Computer Science, or related field; or equivalent combination of education and experience.
• 6-10+ years of IT experience supporting production cloud and Linux systems.
• Demonstrated AWS…