Genomics Biomedical Technician

Overview

CEDARS-SINAI has partnered with iHire to reach top talent for their opening below. Check it out and apply via iHireBiotechnology today! The Applied Genomics, Computation & Translational Core is looking for a Biomedical Technician to join the team! The Cedars-Sinai Applied Genomics, Computation & Translational (AGCT) Core is an automated, high-throughput genomics facility equipped with the latest next-generation sequencing technologies. We specialize in single-cell and spatial omics, utilizing platforms including 10x Genomics (Chromium X, Xenium Analyzer, Visium Cyt Assist), Parse Biosciences, Scale Biosciences, Illumina, Singular Genomics G4X, and Bruker CosMX SMI.

We also offer expertise in long-read sequencing via Oxford Nanopore Technologies (Prometh

ION 24, MinION) and high-throughput short-read sequencing on the Illumina Nova Seq X Plus. We provide comprehensive support covering sample preparation, library construction, and diverse sequencing applications including bulk cell RNA-Seq, WGS/WES, ATAC-Seq, and metagenomics. The AGCT Core also delivers extensive bioinformatics analysis. Standard pipelines are established for primary data processing across all services, encompassing read alignment, quality control, expression quantification, variant calling, and peak calling.

We also provide downstream analysis packages to help analyze these data in the context of the researchers experimental design. We actively collaborate with investigators to develop sophisticated or custom computational solutions for specific research questions, including advanced analysis for spatial transcriptomics data. Our bioinformatics support extends to results interpretation, generation of publication-ready figures, and drafting manuscript methodology. To learn more please visit Applied Genomics, Computation & Translational Core | Cedars-Sinai.

Are you ready to be a part of breakthrough research?

• Performs a variety of project-specific process development tasks for multiple clients following standard operating procedures (SOPs).
• Maintains good documentation in laboratory notebooks, data record/transfer, SOPs, and batch records.
• Drafts standard operating procedures and maintains computer database.
• Verifies samples received, logs samples into systems, and may transport to appropriate environment within the facility for storage following SOPs.
• Performs lab maintenance duties, including glassware cleaning and sterilization.
• Maintains lab equipment and related records.
• Prepares cGMP production room, maintains material inventories, and places orders for equipment and supplies.
• Assists in the operation of specialized equipment and machinery.
• Ensures all activities comply with regulatory guidelines and safety standards, as appropriate.
• Construction of next generation sequencing libraries for bulk cell, single cell, and/or spatial omics using commercially available reagent kits.
• Illumina short-read sequencing and/or Oxford Nanopore Technologies long-read sequencing of NGS libraries.
• DNA/RNA QC via fluorescent quantification and automated electrophoresis.
• Operation of state-of-the-art genomics equipment including NGS sequencers, automated liquid handlers, and tissue imagers, as well as standard laboratory equipment such as thermal cyclers, centrifuges, and qPCR machines.
• Mathematical calculations, including fold dilution, normalization, and conversions.
• Understand, analyze, and interpret DNA/RNA/NGS library/sequencing QC results.
• Liaise with post-doctoral, doctoral, and staff researchers, clinical investigators, and principal investigators to provide quality customer service.
• Handle multiple demands and/or manage complex and competing priorities, pivoting as needed based on current needs in a dynamic environment.
• Apply advanced knowledge of science/learning/specialized intellectual instructions to analyze, interpret, or make deductions from varying facts or circumstances.
• Provide and/or support a level of work excellence and accuracy; recognize and address flaws or errors that others may overlook.
• Regular oral and written communication with team members and team lead.
• Accurate and detailed electronic documentation of work performed and results obtained.
• Work independently as part of a team under direct supervision of a team lead.
• Observe and comply with all safety standards and procedures.

• Associate Degree or College Diploma in Biology, Biochemistry, or a related science or engineering field.
• Minimum of 1 year of experience working in a laboratory or biotechnology environment.
• Experience with biomedical equipment, including maintenance and/or testing.

• Bachelor’s Degree in Biology, Biochemistry, or a related science or engineering field.