Postdoctoral Research Associate, Peter Gorer Department of Immunobiology

Offer Description

About Us

The GSTT Asthma Service based at Guy’s Hospital is home to the largest cohort of severe asthma and EGPA patients receiving biologic therapies in the UK offering a unique opportunity to take part in translational research in these diseases.

The Jackson Lab within the Peter Gorer Department of Immunobiology, SIMS is focussed on (i) exploring the role of eosinophilic and T2 inflammation in asthma and related conditions both in the stable state and during exacerbation (ii) understanding the mechanisms that underpin the heterogeneity in response to anti‑T2 therapies in asthma and conditions including EGPA and eosinophilic pneumonia.

Over the last 5 years the Jackson Lab has obtained over £5m in grant funding and published over 50 original research manuscripts.

About the role

This role is for a scientist who has obtained a PhD and has already accumulated some post‑doctoral experience in the field of type 2 immunity as applied to asthma and related upper and lower airway conditions. The applicant should have a thorough understanding of respiratory immunology and particularly eosinophilic and T2 immune pathways including mast cell, Th2, ILC2 and epithelial related processes in asthma.

It is expected that the scientist has first‑hand experience of processing and analysing airway samples including cell culture.

The successful candidate will have a thorough understanding of respiratory immunology and particularly eosinophilic and T2 immune pathways in diseases such as asthma. The scientist should have first‑hand experience of processing and analysing airway samples including cell culture.

The successful applicant will be joining a well‑established and highly productive clinical and translational asthma research group at King’s College London based on the Guy’s Hospital Campus. The Jackson Lab is closely integrated into the regional NHS Severe Asthma and EGPA clinics allowing access to airway and blood samples from a large cohort of patients.

This group has led on several large multicentre phase 3 and phase 4 clinical trials of biologic therapies in asthma as well as real‑world studies of biologic therapies in both asthma and EGPA.

The applicant will work alongside clinical fellows undertaking mechanistic projects in severe asthma as well as other post‑doctoral scientists working in this group. They will lead on several aspects of ongoing mechanistic projects aligned to phase 3 and phase 4 clinical trials of biologic therapies in asthma.

This is a full‑time post 35 hours per week, and you will be offered a fixed‑term contract until 31/12/27.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

• PhD qualified in relevant subject area *
• Experience with airway cell culture
• Comprehensive understanding of T2 immunity in asthma
• Experience with airway proteomics and transcriptomics

* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

• Understanding of spatial transcriptomics
• Experience with CyTOF

Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.

We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

As part of this commitment to equality, diversity and inclusion and through this appointment process, it is our aim to develop candidate pools that include applicants from all backgrounds and communities.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the person specification section of the job description. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.

Grade and Salary:£45,031 - £49,871 per annum, including London Weighting Allowance
Job :135565
Close Date:25-Jan-2026
Contact Person:David Jackson
Contact Details: