Clinical Trials Monitor

Clinical Trials Monitor

The closing date is 27 January 2026

The Clinical Trials Monitor post is based in the Research & Development Department with a focus to lead on the monitoring of clinical trials sponsored by Chelsea and Westminster Hospital NHS Foundation Trust (CWFT).

The post holder will report directly to the Regulatory Compliance Manager and work with them for study set up, routine monitoring and the close out of both clinical trials of investigational medicinal products (CTIMPs) and non-CTIMPs on behalf of CWFT.

The Post holder will support the CWFT Sponsor Team and Chief Investigators by monitoring studies in accordance with the monitoring plan, protocol, regulatory requirements, SOP's and GCP. Conducting on-site, remote and central monitoring visits as outlined in the monitoring plans and writing reports, tracking non-compliances, and escalating findings following the visits. The post holder will be the main point of contact for sites hosting CWFT studies and will also support the CWFT Sponsor Team in improving sponsorship processes and monitoring strategy.

To be responsible for the monitoring, conduct, progress review and documentation of Trust sponsored clinical trials by reviewing sponsor and site trial documents and performing source document verification (SDV) in accordance with ICH GCP guidelines.

To act as a primary contact for external sites participating in Trust sponsored trials, supporting trial set up, management, data monitoring and consolidation and close-out visits.

Chelsea and Westminster Hospital NHS Foundation Trust is one of England's top-performing and safest trusts. We operate two main acute hospital sites--Chelsea and Westminster Hospital and West Middlesex University Hospital--along with award-winning clinics across North West London.

Our nearly 7,500 staff care for a diverse population of 1.5 million, providing full clinical services, including maternity, A&E, and children's services, plus specialist HIV and sexual health clinics. The Care Quality Commission rates us 'Good' in safety, effectiveness, care, and responsiveness, and 'Outstanding' in leadership and resource use.

We continually invest in our facilities, including a £30m expansion of critical care at Chelsea and Westminster and an £80m Ambulatory Diagnostic Centre at West Middlesex.

We welcome applications for flexible working arrangements, accommodating requests where possible to support our staff and patient needs.

The Trust is committed to equality and welcomes applications from all, regardless of background. Adjustments can be made for disabled candidates. Early application is advised as vacancies may close once sufficient applications are received. If you haven't heard from us within three weeks of the closing date, your application was likely unsuccessful. Employment is subject to a six-month probationary period.

Some roles may require weekend shifts at multiple sites.

1. Planning and organisation

• To be responsible for the monitoring, conduct, progress review and documentation of Trust sponsored clinical trials by reviewing sponsor and site trial documents and performing source document verification (SDV) in accordance with ICH GCP guidelines.
• Initiate and oversee monitoring plans for Trust sponsored clinical trials
• Ensure that the monitoring plans for multi-site clinical trials are reviewed and approved prior to trial initiation.
• Ensure that all appropriate medication manufacture, supply and release documentation is in place before the trial commences.
• To ensure all trial related Standard Operational Procedures (SOPs) are adhered to and in particular the recording, reporting and tracking of Serious Adverse Events and Adverse Reactions.
• Coordinate trial initiation visits before any research activity commences, to include review of facilities where trial activity is taking place and obtaining a signed Investigator agreement highlighting research responsibilities.
• Ensure each trial has a system for documenting IMP drug accountability and traceability.
• Ensure end of trial reporting and publishing of results is conducted according to regulation.

2. Analytical

• Assi…