Scientist​/Senior Scientist - Histology and Target Expression; FTC

Scientist/Senior Scientist - Histology and Target Expression (12 month FTC)

Engitix Therapeutics is a pioneering biotech dedicated to unlocking extracellular matrix biology to develop transformative therapies in fibrosis and oncology. We are seeking a Scientist or Senior Scientist (12‑month fixed‑term contractor) to provide expert histology and tissue‑based target validation support across our discovery pipeline.

In this role, you will apply histology, immunohistochemistry and immunofluorescence approaches to characterise therapeutic targets in disease‑relevant models and human tissues. Your work will generate high‑quality data to support discovery programmes and inform decision making. This is an exciting opportunity for an experienced industry scientist to contribute hands‑on, impactful science across multiple programs in a dynamic biotech environment.

• Design and execute experiments to confirm and characterise therapeutic target expression using tissue‑based approaches.
• Lead hands‑on delivery of histology, immunohistochemistry (IHC) and immunofluorescence studies to assess target expression, localisation, and regulation in disease‑relevant models and human tissues.
• Analyse, interpret and present histological data to support target validation and discovery decision making.
• Optimise and apply advanced tissue technologies such as multiplex IF, digital pathology and image analysis workflows.
• Maintain robust, reproducible and well documented histology workflows.
• Ensure high standards of data integrity, quality and traceability in line with Engitix standards.
• Provide histology expertise to discovery teams, working closely with biologists, programme leads and data scientists.
• Communicate results clearly to internal stakeholders to support scientific decisions.

• PhD (or equivalent experience) in Molecular Biology, Cell Biology, Pathology, or related discipline.

• 3-5+ years’ experience in the biotechnology or pharmaceutical industry (Scientist: 3+ years; Senior Scientist 5+ years), with strong hands‑on expertise in histology and tissue‑based target expression studies.
• Experience supporting drug discovery programmes with histological data.
• Practical experience with digital pathology and image analysis platforms (e.g. HALO, Visiopharm and Vectra).
• A strong understanding of relevant regulations and ethical guidelines related to biospecimen research, including HTA and GDPR requirements.

• Execution:
  Delivers reproducible high‑quality data.
• Scientific Judgement:
  Applies histology expertise to guide experiments and interpret data.
• Collaboration & Communication:
  Works across stakeholders and teams and communicates findings clearly.
• Adaptability:
  Thrives in a fast‑paced biotech environment.
• Desirable:
  Experience in oncology, tissue fibrosis and immune microenvironment pathology.

At Engitix, you’ll be part of a mission‑driven biotech pioneering extracellular matrix biology to develop transformative therapies in fibrosis and oncology. This fixed‑term contract offers the chance to apply histology expertise to impactful discovery programmes, working alongside talented scientists in state‑of‑the‑art laboratories at The Westworks, White City.

Join us and contribute to a mission that combines scientific excellence with the drive to bring new medicines to patients who need them most.

Engitix is a growing biotech company based in White City Place, West London. We are dedicated to developing better therapies for advanced fibrosis and solid tumours by leveraging our pioneering extracellular matrix (ECM) platform. Our platform allows the synthesis of realistic in vitro 3D models that serve as tools to transform our ability to identify new targets and biomarkers, determine mechanisms of action and more accurately predict the efficacy of therapeutic candidates.

Join us today in our mission to create a healthier future for patients with life‑threatening diseases such as fibrosis and cancer.

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