Senior Technical Program Manager

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life‑changing medicines with an ambition to solve all disease.

The future is coming – a future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.

Isomorphic Labs (Iso Labs) was launched in 2021 to advance human health by building on and beyond the Nobel‑winning Alpha Fold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform, and develop innovative medicines to treat and cure some of the world’s most devastating diseases.

We have built a world‑leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting‑edge capabilities to advance rational drug design.

Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.

As a Technical Program Manager, you will be the operational backbone of our research initiatives, bringing structure to the highly experimental world of AI‑driven drug discovery. Partnering closely with our Research Scientists and ML Engineers, you will ensure that complex research roadmaps move from theoretical concepts to tangible technical milestones.

• Take full ownership of multiple, concurrent research roadmaps, ensuring that milestones are clearly defined and actions between teams are managed effectively.
• Facilitate clear and open communication between Research Scientists, ML Engineers and other teams, ensuring full alignment on requirements and project timelines at all times.
• Design and implement frameworks to track progress in experimental environments where the path forward isn’t always linear.
• Set the operational rhythm of technical syncs, compiling agendas that bridge the gap between code and Life Sciences, and ensuring action items are closed out.
• Identify potential bottlenecks in the research pipeline (e.g., data availability, compute resources) and proactively work with senior TPMs to resolve them before they impact the roadmap.

• c. 4–5 years’ experience in technical program coordination or project management within a tech‑forward, life sciences or research‑driven environment.
• A solid professional or academic background in Biology, Chemistry, or Computational Biology. You need to understand the why behind the research you are coordinating.
• Comfortable working closely with Machine Learning Engineers; you understand the basic lifecycle of model development and data pipelining.
• You are comfortable prioritising in an ambiguous environment and don’t require a pre‑defined playbook to be effective.
• Exceptional organisation skills with the ability to manage multiple competing priorities across different domains (specifically Science vs. Engineering).

• Experience using tools like Jira or Linear to manage research workflows.
• Previous experience in a high‑growth "Tech Bio" or Biotech startup.

Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future‑making science every single day.