Pilot Plant Downstream Engineer

Overview

The work we do at Eurofins matters, and so do our employees. We focus on professional growth and provide the ability to break into the biopharmaceutical industry. We offer work-life balance and a competitive benefits package.

Eurofins Scientific is an international life sciences company providing analytical testing services across multiple industries to make life and the environment safer, healthier and more sustainable. Eurofins works with major companies to ensure products are safe, ingredients are authentic, and labeling is accurate. It is a global leader in food, environmental, pharmaceutical and cosmetics testing, agroscience CRO services, genomics, discovery pharmacology, forensics, CDMO, advanced materials, and clinical studies support.

If you’re looking for a rewarding career, apply with us today.

The Pilot Plant Downstream Engineer plays a key role within R&D Pilot Operations, serving as a technical link between lab-scale process development and full-scale GMP manufacturing. This engineer will independently execute routine and complex downstream purification operations, contribute to experimental planning, support documentation development (SOPs, batch records, reports), and perform data analysis using Spotfire or equivalent tools. The role requires expertise in downstream operations such as harvest clarification, chromatography, filtration, and buffer preparation.

Experience with AKTA systems and Unicorn software is preferred; familiarity with upstream pilot-scale operations is valued.

• 80% – Pilot-Scale Downstream Operations
  • Execute non‑GMP downstream purification activities at pilot scale (50–1000 L) to support new product development, material supply, process characterization, and demonstration batches across the full development lifecycle, including post‑launch programs.
  • Partner with Process Development and Manufacturing Sciences to troubleshoot downstream issues and contribute to large‑scale process investigations.
  • Manage operational details such as long‑lead material tracking, sample planning, equipment scheduling, material ordering, and vendor coordination.
  • Independently collect, interpret, and trend process data; identify deviations, patterns, and opportunities for optimization.
  • Present results, technical challenges, and proposed solutions in project and departmental meetings.
  • Contribute to the drafting and revision of pilot‑scale procedures, batch records, and technical documentation supporting process transfers and scale‑up.
  • Support global technology transfer by providing technical insights, process data, and operational expertise.
  • Assist with authorship of technical reports, study protocols, internal presentations, and—when applicable—scientific abstracts or conference materials.
• 20% – Technology & Digital Innovation
  • Identify, evaluate, and integrate new pilot‑scale technologies and digital tools to enhance R&D operational flexibility and downstream process capability.
  • Drive continuous improvement initiatives focused on efficiency, process robustness, and advanced data analytics.

• Bachelor’s degree in Chemistry, Biology, Engineering, Pharmacy, or related field with 2+ years of relevant industry experience, or a Master’s degree (industry experience preferred).
• Hands‑on experience with downstream purification (chromatography, UF/DF, TFF, depth/sterile filtration).
• Experience supporting non‑GMP pilot‑plant operations at 50–1000 L bioreactor or equivalent downstream scale.
• Working knowledge of AKTA chromatography systems and Unicorn software preferred.
• Strong scientific problem‑solving and data analysis skills.
• Excellent communication and documentation abilities.
• Effective collaborator able to work across multi‑functional teams.
• Strong organizational skills with the ability to manage multiple priorities in a fast‑paced environment.
• Proficiency with laboratory and pilot‑scale equipment; upstream familiarity is a plus.
• Ability to wear PPE and perform physical tasks including lifting up to 25 lbs, standing for up to 4 hours, and climbing ladders or accessing equipment platforms.
• Authorized to work in the United States indefinitely without restriction or sponsorship.

• 10-15 Minute Phone Interview with Region Recruiter
• 45-60 Minute Virtual Interview with Manager and/or Group Leader
• 45-60 Minute Onsite to Meet the Team

The position is Full Time, Monday-Friday, 8am-5pm. Candidates currently living within a commutable distance of Lexington, MA, are encouraged to apply.

• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Yearly goal-based bonus & eligibility for merit-based increases
• Hourly rate is between $30-34

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.