Area Engineer, Biologics Building - Lilly Medicine Foundry

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

The Area Engineer is the site Subject Matter Expert (SME) for the Biologics Building (BB) and the associated ancillary systems within the FUME (Facilities, Utilities Maintenance & Engineering) organization. During the project phase, the Area Engineer will be a key player in the cross‑functional project team assisting in the design, construction, commissioning, qualification, start‑up and operational readiness of all systems within the Lilly Medicine Foundry’s BB.

During day‑to‑day operation, the Area Engineer will effectively, reliably, and cost‑consciously oversee and maintain the site’s BB and ancillary systems, ensuring all systems are in compliance, in control and fit for use to meet internal customer and business needs. The Area Engineer will also drive continuous improvement initiatives and manage both annual operating expenses and local capital investments for requested revisions or new functionality.

• Process Rooms
  • ISO 7/8 Flexible Spaces
  • Single Use Bioreactors (SUBs) (50L – 2000L)
  • Single Use Mixers (SUMs)
  • Chromatography Columns
  • Organic Solvents
  • Bio Safety Cabinets (BSCs)
  • Gas / Temperature Control Units (TCUs)
• Material Dispensing
  • Cold room(s) / freezers
  • BSC’s and fume hoods
  • Drum handling
• Media Prep
  • Agitated vessels
  • Portable SUMs
  • TCUs
• Buffer Prep
• Cell Bank
  • Cryovial Storage System
• Process Utility Areas
• Clean in Place (CIP)
• Caustic Dilution System
• Water for Injection (WFI)
• Waste Systems
• Compressed Gas Systems
  • Oil Free Compressed Air
  • Nitrogen (N2) – Bulk Liquid
  • Oxygen (O2) – Bulk Liquid
  • Carbon Dioxide (CO2) – Bulk Liquid
• Ensure assigned processes are aligned with industry and Lilly standards
• Support risk assessment exercises (e.g., FMEA)
• Participate as required in teams, committees, or other groups to achieve FUME’s goals

• Lead or participate in projects/changes for all BB systems, including design, verification activities (IV/OV/PQ), as user representative for capital projects or delivery agent for local projects.
• Develop proper documentation (User Requirement Specifications, test cases, etc.) to demonstrate systems are properly installed, qualified and started up and remain in control.
• Contribute to process resource assessment, capital plans, expense budgets, and prioritize as appropriate.

• Monitor all BB systems and maintain KPIs to assure proper operation and compliance.
• Act as the single point of contact for the BB to resolve deviations, change controls and CAPAs with Operations, Process Engineering, Supply Chain, HSE and Quality Assurance.
• Collaborate within FUME to implement efficient maintenance and reliability techniques aligned with global engineering standards.
• Apply hands‑on problem‑solving skills to rapidly resolve equipment failures, conduct RCA and guide operations personnel.
• Provide internal customer consultation and notifications on critical utilities and equipment issues.
• Ensure corrective/preventive maintenance items are tracked and completed by required dates.
• Provide technical assistance to FUME, HSE, Process Engineering and Operations personnel.
• Lead or participate in capital projects/changes for all BB systems, including project…