Associate researcher in proteomics and mass spectrometry

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Are you looking for an exciting multi-disciplinary position where analytical experimental skills and mass spectrometry instruments are used? The Proteomics Core Facility (PCF) is an open access facility organized within the Core Facilities, Sahlgrenska Academy at the University of Gothenburg,(Use the "Apply for this Job" box below). The Facility is a biological mass spectrometry (MS) platform that provides scientific expertise and advanced instrumentations for high quality research support.

The MS platform is part of the national BIOMS infrastructure, supported by the Swedish Research Council as well as a part of the Sci Life Lab  national resource of unique technologies, within the Glycoproteomics and MS Proteomics unit.
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PCF offers a wide range of proteomic research support, from small- to large-scale mass spectrometry–based studies for protein quantification and comparative analysis, to specialized applications in glycomics and glycoproteomics. We use Orbitrap and tims

TOF mass spectrometers interfaced with LC systems to answer advanced biological questions in natural sciences and in medicine to support the discovery of biomarkers and disease-associated pathways.

Responsibilities

• Designing and planning experiments, executing, and managing user-requested proteomics and other MS-based research projects, including hands‑on laboratory work.
• Operation of the MS instruments, Orbitraps (Thermo Scientific) and tims‑TOFs (Bruker) interfaced with nano‑LCs.
• Performing data analysis and interpretation using established proteomics software and tools, such as Proteome Discoverer, Spectronaut, Skyline, Byonic, Perseus and R‑based Shiny applications.
• Documenting experiments and method development for project tracking and publications; staying updated with current technologies and scientific literature; and participating in scientific conferences.
• Providing scientific support and consultation to internal and external users throughout all stages of proteomics projects.

A key focus of the position will be the planning and execution of proteomics and MS experiments in close collaboration with platform users and the team members, as well as sharing knowledge within the facility team. You will take part in multiple projects applied to different biological materials and research questions.

The bioinformatic/statistic component of the proteomic pipeline is an important part of the work, to be able to assist the users in interpretation and integration of the proteomics data into biology. The position also involves surveying, implementing and optimizing new technological approaches, experimental protocols and software related to proteomics and MS.
Qualifications We are seeking an experimental scientist with a documented strong background and relevant expertise in proteomics and high resolution MS, including identification, quantitative and/or post‑translational modification studies.

• The applicant must have hands‑on experience in proteomics and mass spectrometry, including the complete workflow from sample preparation to MS analysis.
• The successful candidate shall have knowledge and experience with MS data analysis and major proteomic software packages, e.g. Proteome Discoverer and Spectronaut, DiaNN, Frag Pipe etc.
• The candidate shall be able to present previous work in proteomic studies.
• Knowledge in manual interpretation of MS spectra as well as programming/writing scripts is highly desirable and a merit.
• Knowledge in post‑translational modifications, glycoproteomics or glycomics is a merit.
• Excellent communicational and organizational skills, strong team working ability and a service‑minded attitude are essential and will be evaluated in the team as part of the selection process.
• Flexibility, problem‑solving capabilities and ability to adapt to rapid changes together with a deeper understanding of academic research is a merit and will be evaluated together with the team.

Employment The employment is a full-time (100%), permanent position, placed at Proteomics Core Facility within the Core Facilities at the University of Gothenburg. A probationary employment period of 6 months may be applied.

Start date as soon as possible based on agreement.
Selection process

Applicants will be evaluated based on submitted documents, interviews, and references.
Contact information for the post

For questions regarding the position, you are welcome to contact Carina Sihlbom Wallem, head of unit at Proteomics Core Facility, on  or carina.sihlbom.
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