Principal Supply Chain Architect

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well‑being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Principal Supply Chain Architect

The Principal Supply Chain Architect is the senior-most individual contributor responsible for end‑to‑end architectural strategy and governance for Supply Chain with key accountability for modernization efforts. This role has enterprise‑wide accountability for defining, evolving, and governing the target‑state Supply Chain architecture across planning, execution, distribution, automation, integration, data, and analytics. Operating with broad autonomy, the role directly enables the Supply Chain Modernization Office by ensuring that modernization initiatives are architecturally sound, scalable, secure, and aligned with long‑term business outcomes.

The role also ensures a cohesive end‑to‑end view coordinating with other architects within Supply Chain and adjacent technologies/processes. The Principal Architect influences multi‑year investment decisions, mitigates enterprise risk, and serves as a trusted advisor to senior Supply Chain and Technology leadership. This role is key to bringing innovative technologies (including AI) to Supply Chain. This role reports to the MT Supply Chain Modernization Sr Director with a dotted line to the Supply Chain Technology Vice President.

• Own and maintain the end‑to‑end Supply Chain target architecture, spanning:
• ERP Systems
• Planning platforms
• Execution systems (WMS, TMS, LMS)
• Distribution center automation and robotics
• Integration, data, and analytics platforms
• Quality
• Define architectural direction that supports multi‑year modernization roadmaps while ensuring operational stability of legacy platforms.
• Establish reference architectures, principles, and patterns adopted across the Supply Chain portfolio.
• Act as the primary architecture leader supporting the Supply Chain Modernization Office.
• Translate modernization strategy into architecturally sequenced roadmaps, identifying dependencies, risks, and decision points.
• Ensure consistency and alignment across all modernization initiatives, regardless of delivery team or integrator.
• Incorporate innovative processes and technologies (including AI / IOT) across supply chain processes.
• Chair or provide authoritative guidance in architecture design reviews for major Supply Chain initiatives.
• Set and enforce architectural standards across platforms, integrations, security, and data.
• Approve or influence key technology decisions with enterprise and financial impact.
• Ensure regulatory and compliance requirements (e.g., DSCSA) are architecturally embedded into solutions.
• Partner with the Modernization Office, Finance, and Enterprise Architecture to support CAR development, option analysis and trade‑off decisions, and platform rationalization strategies.
• Provide clear architectural recommendations that balance cost, risk, scalability, and long‑term value.
• Identify opportunities to reduce total cost of ownership through reuse, standardization, and simplification.
• Align and design architectural artifacts across the Supply Chain Team (heatmaps, design documents, review board decks, etc).
• Serve as a trusted architecture advisor to Supply Chain, Technology, and Enterprise Architecture executives.
• Communicate complex architectural concepts in business‑relevant terms for executive forums and steering committees.
• Drive alignment across Supply Chain Operations, Product, Enterprise Architecture, and external partners.
• Mentor and guide Lead and Solution Architects across Supply Chain domains.
• Elevate architectural maturity across the organization by promoting best practices and reuse.
• In…