Associate VP - Health Economics and Outcomes Research; HEOR - Global CMH

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

We are seeking an exceptional leader to lead our Real-World Evidence (RWE) function for Lilly Cardiometabolic Health (CMH). This individual will report to the President of Lilly CMH and sit on the CMH Leadership Team, with responsibility for shaping our RWE strategy and portfolio of projects, managing a team of RWE scientists, delivering strong evidence to support registration plans, new uses and NILEX, and demonstrate the value of our medicines.

This includes our portfolio of groundbreaking therapies across obesity, diabetes, cardiovascular disease, and related metabolic conditions.

• Provide strategic oversight of the cardiometabolic RWE portfolio, aligning evidence generation with business objectives
• Work collaboratively with cross-functional partners including Medical Affairs, Commercial, Patient/Regulatory Affairs (PRA), and Development teams to identify evidence gaps and establish project priorities
• Oversee the design, execution, and delivery of a diverse portfolio of RWE studies across cardiovascular disease, diabetes, obesity, and metabolic disorders
• Ensure all RWE projects are delivered on time, within budget, and to the highest scientific standards
• Execute publication and communication strategies that maximize scientific impact and visibility of RWE findings

• Recruit, develop, and manage a high-performing team of RWE scientists with diverse expertise in epidemiology, biostatistics, health economics, and outcomes research
• Foster a culture of scientific excellence, innovation, and collaboration within the RWE team
• Provide mentorship and career development opportunities for team members
• Build team capabilities in emerging RWE methodologies and data sources

• Forge strategic partnerships with leading academic institutions, research organizations, and healthcare data companies to access novel data sets and advanced analytic capabilities
• Identify and evaluate external collaborators with unique data assets (e.g., EHR systems, claims databases, registries, wearable device data)
• Negotiate and manage collaboration agreements that advance Lilly's RWE objectives
• Represent Lilly in external scientific forums and maintain relationships with key opinion leaders in real-world evidence

• Generate real-world evidence to support regulatory submissions and post-approval requirements, working closely with development teams
• Identify new therapeutic uses and potential New Indication for a Licensed Product (NILEX) opportunities through analysis of real-world data patterns
• Demonstrate the clinical and economic value of Lilly's cardiometabolic medicines through rigorous comparative effectiveness research, health outcomes studies, and health economic analyses
• Translate RWE findings into actionable insights for commercial strategy and medical affairs initiatives

• Ensure all RWE studies adhere to best practices in study design, analysis, and reporting (ISPOR guidelines, STROBE, etc.)
• Develop and implement innovative methodologies for causal inference, comparative effectiveness, and patient outcomes assessment
• Drive scientific disclosure through high-impact publications, presentations at major conferences, and engagement with the scientific community
• Stay current with evolving regulatory guidance on RWE and ensure compliance across all studies

• PhD, Pharm
  
  D, MD, or equivalent advanced degree in epidemiology, health services research, outcomes research, biostatistics, or related field
• Minimum 10 years of experience in real-world evidence, outcomes research, or epidemiology within the pharmaceutical or biotech industry

• Proven track record of leading RWE teams and delivering high-quality evidence generation programs
• Deep expertise in real-world data sources (claims, EHR, registries) and advanced analytic methods for observational studies
• Strong understanding of cardiometabolic diseases and their treatment landscape
• Demonstrated success in establishing and managing external research partnerships
• Experience supporting regulatory submissions with RWE (FDA, EMA)
• Excellent scientific writing and communication skills with multiple peer-reviewed publications
• Strong leadership, collaboration, and influence skills across matrixed organizations
• Experience with novel data sources…