Sr Scientist - Radiopharmaceutical Development & CMC

Working with Us

Challenging. Meaningful. Life-changing. Those aren‑t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

Rayze Bio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. Rayze Bio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, Rayze Bio aims to be the global leader in radiopharmaceuticals.

We are seeking a highly motivated Sr. Scientist to lead the development and optimization of radiopharmaceutical drug products and radioisotopes. This position plays a pivotal role in driving preclinical development of innovative drug products aimed at treating various cancers. The successful candidate will contribute to shaping and advancing our Chemistry, Manufacturing, and Controls (CMC) strategy.

Essential duties and responsibilities include the following. Other duties may be assigned.

• Design, plan and execute scientific experiments for pre‑clinical development of radiopharmaceuticals.
• Drive CMC process development and optimization for clinical drug products, including formulation lock and robust process definition, ensuring scalability and compliance with regulatory standards.
• Design, plan and execute scientific experiments for scale up and automation of drug products and API manufacturing processes.
• Interpret complex experimental data, draw scientifically rigorous conclusions, and communicate findings in technical reports, regulatory documentation, and presentations for internal and external stakeholders.
• Author technical reports and source documents to support regulatory filing.
• Author CMC sections for IND/NDA for FDA submissions, and support regulatory filing in other jurisdictions, e.g. EMA, Health Canada, etc.
• Support technology transfer of drug products and API from preclinical stage to clinical manufacturing.
• Collaborate cross‑functionally with Regulatory, Quality, Supply Chain, Clinical, and R&D teams to ensure alignment with corporate goals.
• Manage and prioritize research projects, oversee third‑party vendors, and mentor junior scientists and associates.
• Provide support for commercialization of radiopharmaceuticals.
• Up to 20% of travel required.

• Ph.D., M.S., or B.S. in Chemistry, Chemical Engineering, Pharmaceutical Sciences, or a related field, with requisite industry experience.
• 5+ years of experience in drug development, manufacturing, CMC or related fields in a pharmaceutical industry, preferably radiopharmaceuticals.

• Strong understanding of GMP, FDA/EMA regulations, and ICH guidelines.
• Strong problem‑solving abilities and the ability to manage multiple projects in a fast‑paced environment.
• Excellent project management and cross‑functional collaboration skills.
• Excellent technical writing skills.

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 15 pounds. Specific vision abilities required by this job include close vision and distance vision. This is a position that requires working in a laboratory environment, protective clothing, gloves, and…