Computational Biologist; QSP Expertise; Mid-Level

About CFD Research: Since its inception in 1987, CFD Research has delivered innovative technology solutions within the Aerospace & Defense, Biomedical & Life Sciences, Intelligence & Sensing, and Energy & Materials industries. CFD Research has earned multiple national awards for successful application and commercialization of innovative component/system technology prototypes, multi-physics simulation software, multi-disciplinary analyses, and expert support services. Based in Huntsville, Alabama where laboratory facilities and headquarters are located, CFD Research also has office and laboratory facilities in Dayton, Ohio, prototyping test and evaluation facilities in Hollywood, Alabama, and office facilities in Fort Walton Beach, Florida.

CFD Research is an ISO
9001:

AS9100D registered company and is appraised at CMMI Level II for Services. CFD Research is a 100% ESOP (employee‑owned company) recognized in Inc. Magazine's Inc
5000 as a top growing company for four of the last five years. Learn more at

We are seeking a highly motivated Mid‑Level Computational Biologist with expertise in Quantitative Systems Pharmacology (QSP) and a strong background in PK/PD modeling and physiologically‑based pharmacokinetic (PBPK) modeling. This is an exciting opportunity to contribute to groundbreaking research, working on projects funded by the NIH, FDA, DoD and pharma. The successful candidate will work in a collaborative, multidisciplinary environment, contributing to the development of cutting‑edge computational models that integrate biological and pharmacological data to support drug development and regulatory decision‑making.

• Develop and apply QSP models to investigate biological and pharmacological systems.
• Develop and apply PK/PD modeling and PBPK modeling to support drug development, safety, and efficacy studies.
• Collaborate with experimentalists, clinicians, and other computational scientists to design and interpret modeling studies.
• Contribute to the preparation of scientific reports, presentations, and publications.
• Stay current with advances in computational biology, pharmacology, and regulatory science to incorporate best practices and innovative approaches.

• PhD or Master’s degree in Computational Biology, Pharmacology, Systems Biology, Engineering, or a related field.
• 2‑5 years of experience in QSP modeling, PK/PD modeling, and/or PBPK modeling.
• Proficiency with relevant software tools and programming languages (e.g., MATLAB, R, Python, Bio Gears).
• Experience with data integration from various biological and clinical sources.
• Strong communication skills and the ability to work well in a multidisciplinary team.
• Experience working on government‑funded projects is a plus.
• U.S. Citizenship is required.

• Expertise in model calibration, validation, and sensitivity analysis.
• Familiarity with regulatory guidelines related to modeling and simulation.
• Experience working with clinical trial data and preclinical studies.

• Opportunity to work on impactful research funded by the NIH, FDA, DoD and Pharma.
• Collaborate with a dynamic team of scientists, clinicians, and regulatory experts.
• Flexible work environment with opportunities for professional growth and development.

This role is based in the Huntsville, AL area, and is 100% onsite.

CFD Research offers competitive salaries and excellent employee benefits, including an employer matching 401(k) and Employee Stock Ownership Plan (ESOP). CFD Research offers our Full‑Time, permanent employee‑owners a highly competitive insurance package, including medical, vision, and dental insurance. Additionally, we offer company paid leave, compensation time, parental leave, long‑term and short‑term disability, accidental death and dismemberment, and life insurance. Part‑Time and Temporary employee‑owners may receive partial or reduced benefits and leave time based on their employment status level.

Performance appraisals occur twice a year and annual pay increases are based upon corporate goals, personal development, performance, and outstanding achievements. In addition, group and individual bonuses are awarded for exceptional performance.

CFD Research is an EO employer – Veterans/Disabled and other protected categories.