Research Assistant II​/Cancer Systems Imaging

Overview

The mission of The University of Texas MD Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research, and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees, and the public.

The Department of Cancer Systems Imaging is seeking a Research Assistant II to join the Frigo Laboratory. This role supports innovative cancer research by performing complex laboratory experiments, developing and optimizing protocols, supporting animal studies, and contributing to data analysis and presentation. The ideal candidate will bring strong technical expertise, exceptional organization, and a commitment to advancing cancer discovery.

The ideal candidate will have a bachelor's degree and one year of scientific or experimental research work experience.

• Perform animal handling responsibilities including monitoring health, maintaining records, and performing euthanasia and tissue collection according to endpoint criteria.
• Assist with animal-based experiments such as imaging procedures and surgical procedures.
• Extract metabolites from tissue and cultured cells and prepare experimental samples.
• Conduct small tissue grossing, processing, embedding, microtomy, immunohistochemical staining, and cover slipping.
• Optimize SOPs for staining, clearing, and imaging across various tissue types and markers.
• Utilize advanced imaging methods including fluorescent, confocal, and light sheet microscopy.
• Communicate findings to the Principal Investigator and contribute to data presentation for meetings and publications.
• Experience in flow cytometry and Western blotting is highly desirable.
• Perform additional lab duties as assigned.

• Maintain general laboratory operations: restocking supplies, receiving and distributing orders, tracking inventory, and ordering materials.
• Dispose of biohazard waste, maintain glassware, prepare autoclave items.
• Monitor and maintain gas cylinders (O2, CO2), ultra‑low freezers, liquid nitrogen, CO2 and water levels.
• Maintain lab equipment (e.g., centrifuges, pH meters, microfuges) and ensure compliance with safety and OSHA standards.
• Contribute to overall laboratory upkeep, including radioisotope monitoring, reagent aliquoting, and solution preparation.

• Apply scientific knowledge to laboratory techniques using judgment, evaluation, and problem‑solving.
• Stay current on methods through literature review and collaboration with supervisors.
• Develop and implement new procedures to support evolving research needs.
• Maintain accurate records and documentation for all experimental protocols and data.

• Bachelor's degree in a scientific field (biology, biochemistry, or related discipline).
• Experience with animal models and basic surgical techniques required.
• Experience in histology, microscopy, and molecular biology preferred.
• Strong organizational skills, attention to detail, and the ability to work in a collaborative environment.

As one of the world's most respected cancer centers, MD Anderson offers an environment where scientific innovation and meaningful impact come together. Employees enjoy a comprehensive range of benefits and resources designed to support professional and personal growth.

• Comprehensive Health Coverage:
  Medical, dental, vision, and prescription benefits starting on day one.
• Robust Retirement Programs: including a 403(b) with employer contributions and Texas State retirement options.
• Paid Time Off:
  Generous vacation, sick leave, and paid holidays.
• Tuition Assistance & Professional Development:
  Support for continuing education, certifications, and career advancement.
• Wellness Resources:
  On‑site fitness centers, mental health resources, and wellness programs.
• Childcare & Family Support:
  Access to on‑site childcare, backup care, and parental leave benefits.
• Employee Assistance Program (EAP):
  Confidential support for work‑life balance.
• State
  
  Employee Benefits:
  
  Employment with a stable, respected state institution.

Be a…