Manufacturing Supervisor - 2nd Shift

Company Information

You Matter to Cambrex.

Cambrex is a leading global contract development and manufacturing organization (CDMO) that provides drug substance development and manufacturing across the entire drug lifecycle, as well as comprehensive analytical and IND enabling services.

With over 40 years of experience and a team of 2,000 experts servicing global clients from North America and Europe, Cambrex offers a range of specialized drug substance technologies and capabilities, including continuous flow, controlled substances, liquid‑phase peptide synthesis, solid‑state science, material characterization, and highly potent APIs.

Your Work Matters.

• engage in work that matters to our customers and the patients they serve
• learn new skills and enjoy new experiences in an engaging and safe environment
• strengthen connections with coworkers and the community

We’re committed to attracting and nurturing a passionate team of valued professionals in our fast‑paced and growing company. We offer a competitive benefits package that includes healthcare, life insurance, planning for retirement, and more!

Your Future Matters.

Known for our customer‑focused scientific and manufacturing excellence, as well as our strong commitment to quality and safety, we offer a range of career and growth opportunities across our global network of locations. Together with our customers, we aim to improve the quality of life for patients around the world. Start a career where You Matter by applying today!

The Manufacturing Supervisor 2nd Shift is responsible for supporting and overseeing GMP manufacturing activities for development‑stage and commercial‑scale production of Active Pharmaceutical Ingredients (APIs). The role applies a broad knowledge of chemical processing, GMP principles, and operational leadership to ensure successful execution of Phase I–III and commercial manufacturing campaigns, technology transfers, and continuous operational readiness.

• Supervisory responsibilities for Process Technicians including performance management, coaching, and day‑to‑day oversight.
• Responsible for training new employees and developing existing team members to meet both development and commercial manufacturing expectations.
• Upholds a culture of safety, compliance, and operational discipline throughout manufacturing operations.
• Oversees execution of Batch Production Records (BPRs) under cGMP, ensuring all operational steps, quality checks, and in‑process controls are properly documented.
• Performs and/or reviews BPRs, SOPs, deviations, and batch summary reports for development and commercial campaigns.
• Ensures manufacturing readiness for commercial production, including equipment fit checks, raw material availability, and process control verification.
• Provides on‑floor oversight and decision‑making during critical operations such as charging, distillations, crystallization, filtration, drying, and packaging.
• Generates operational protocols and internal/external documentation including SOPs, BPRs, deviations, and summary reports for both clinical and commercial manufacturing.
• Partners with CRD Scientists, Engineering, and Manufacturing Chemists to transfer new and commercialized processes into GMP production.
• Supports implementation and maintenance of process control strategies to ensure robust and reproducible commercial‑scale operation.
• Troubleshoots process and equipment issues; works with Facilities and Engineering to maintain production equipment and recommend improvements or replacements.
• Supports proposals, feasibility assessments, and operational input related to commercial campaign planning.
• Interacts with clients during initial and subsequent manufacturing campaigns; may oversee and escort the Person‑in‑Plant (PIP) during GMP and commercial production.
• Works closely with the Director, Manufacturing to execute development and commercial manufacturing projects, ensuring timelines, quality standards, and contract objectives are met.
• Participates in internal and external audits, including client audits and regulatory inspections; prepares documentation and provides subject matter expertise as needed.
• Ensures operations…