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Senior Director - Cyber Defense Engineering

Job in Harrisburg, Dauphin County, Pennsylvania, 17124, USA
Listing for: AmerisourceBergen Corporation
Full Time position
Listed on 2026-03-12
Job specializations:
  • IT/Tech
    Cybersecurity, Systems Engineer
Salary/Wage Range or Industry Benchmark: 125000 - 150000 USD Yearly USD 125000.00 150000.00 YEAR
Job Description & How to Apply Below
* Define and execute the enterprise cyber defense architecture strategy aligned to threat landscape and risk appetite in collaboration with Cyber Defense senior leadership.
* Develop layered defense models across endpoint, network, cloud, identity, and SaaS.
* Establish and document detection engineering standards and reference architectures.
* Present defense posture maturity, risk trends, and roadmap to executive leadership.
* Establish the enterprise detection engineering program and lead evaluation of new tools and technologies to support the Cyber Defense ecosystem.
* Define logging standards and telemetry requirements across platforms.
* Collaborate & partner with key stakeholder to oversee use case lifecycle management (creation, tuning, retirement).
* Standardize MITRE ATT&CK mapping across detections.
* Reduce false positives while increasing true positive detection rates in collaboration with Cyber Defense teams.
* Drive automation, AI/ML integration, and policy-as-code for response workflows in collaboration with Cloud Security and other senior security leaders.
* Enable automated containment and remediation capabilities.
* Partner with Incident Response and Cyber Counter Adversary leadership for operational efficiency and maturity uplifts.
* Support purple team exercises to validate detection and response effectiveness.
* Integrate strategic, tactical, and operational threat intelligence into engineering roadmap.
* Translate threat actor activity into detection content and control enhancements.
* Support M&A security integrations and divestiture disentanglement.
* Ensure compliance with global regulatory regimes (e.g., HIPAA, GDPR, SOX, FDA/GxP where applicable).
* Establish KPIs, OKRs, and performance dashboards.
* Establish control validation framework.
* Lead breach simulation and continuous control monitoring as needed to support Cyber Defense senior leaders
* Report measurable defense maturity to executive leadership and other senior leaders.
* Lead global team of detection engineers, platform engineers, and automation specialists.
* Establish engineering career paths and succession planning.
* Enterprise financial management and planning experience.
* Follows information security trends within and outside of work with executive leadership to strategize and recommend changes and updates to company.
** Qualifications**:
** Education**:
* Coaching and Mentoring
* Creativity & Innovation
* Decision Making
* Leadership Skills
* People Management
* Planning* Risk-taking

We provide compensation, benefits, and resources that enable a highly inclusive culture and support our team members’ ability to live with purpose every day. In addition to traditional offerings like medical, dental, and vision care, we also provide a comprehensive suite of benefits that focus on the physical, emotional, financial, and social aspects of wellness. This encompasses support for working families, which may include backup dependent care, adoption assistance, infertility coverage, family building support, behavioral health solutions, paid parental leave, and paid caregiver leave.

To encourage your personal growth, we also offer a variety of training programs, professional development resources, and opportunities to participate in mentorship programs, employee resource groups, volunteer activities, and much more. For details, visit

Cencora is a leading global pharmaceutical solutions company that is committed to improving the lives of people and animals everywhere. We connect manufacturers, providers, and patients to ensure that anyone can get the therapies they need, where and when they need them.

We’re a purpose-driven organization, where all of our team members around the world are united in our responsibility to create healthier futures. We work together every day to help our partners bring their innovations to patients worldwide, creating unparalleled access and impact at the center of health.
2.)
** Be Wary of Unrealistic Promises:
** Exercise caution If a job posting offers high salaries and minimal qualifications. Legitimate jobs will have realistic expectations and provide detailed job requirements. Jobs at Cencora can be found on
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Position Requirements
10+ Years work experience
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