Senior Scientist, Cell Therapy

Senior Scientist, Cell Therapy

Are you ready to dive into the world of Cellular Therapy and make a difference in patients' lives? We are on the lookout for a driven and independent Senior Scientist with a knack for Computational Biology applied to Cellular Therapy, Immunology, and Immuno-Oncology. Join our dynamic Cell Therapy Team and contribute to groundbreaking advancements by developing computational models, designing experiments, and interpreting scientific data.

This role is based in Gaithersburg, MD, USA.

• Plan, conduct, and troubleshoot discovery research experiments independently.
• Assess and report data with a clear understanding of its implications within the overall context of drug discovery, independently formulate conclusions, and determine future experiments.
• Design, develop, and deploy AI‑driven machine learning and deep learning models to extract knowledge and insights from structured and unstructured data sources relevant to the development of new therapies.
• Provide technical instruction to the team and allocate administrative work where possible.
• Work collaboratively in a matrix environment.
• Prepare and deliver presentations within the Cell Therapy Unit and across other functions.
• Ensure own work, and work of peers, are compliant with relevant internal AstraZeneca standards and external regulations.

• PhD in relevant disciplines or equivalent experience (e.g. Bioinformatics, Systems Biology, Applied Mathematics, Statistics, Data Science, Computer Science).
• Minimum of 3 years of experience in Cellular Therapy, Immunology, Immuno‑Oncology, Computational Biology, and/or Data Science.
• Proficiency in Python and/or R.
• Prior experience in UNIX‑based systems, high‑performance computing (e.g. SLURM), and large‑scale data management.
• Expertise in omics technologies, capable of processing large‑scale biological datasets (e.g. single‑cell/spatial transcriptomics, in‑house proprietary data sources such as in‑vitro or in‑vivo data).
• Deep understanding of AI, predictive modelling, and statistical methods applied to training of machine learning models.
• Hands‑on expertise in T‑cell functional characterization assays such as in‑vitro cytotoxicity, proliferation, cytokine measurement, and multi‑parameter flow cytometry.
• Ability and motivation to drive projects to completion in a team environment.

• Experience in drug development in an industry setting.

-  USD Annual

The annual base pay (or hourly rate of compensation) for this position ranges from $ to $. Our positions offer eligibility for various incentives—an opportunity to receive short‑term incentive bonuses, equity‑based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program (401(k) plan);

paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at‑will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

07-Jan-2026

12-Jan-2026

AstraZeneca offers an inspiring…