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Histotechnician , 3rd Shift; Tues - Sat

Job in Fremont, Alameda County, California, 94537, USA
Listing for: Personalis
Full Time position
Listed on 2026-01-27
Job specializations:
  • Healthcare
    Medical Technologist & Lab Technician, Clinical Research
Salary/Wage Range or Industry Benchmark: 40 - 50 USD Hourly USD 40.00 50.00 HOUR
Job Description & How to Apply Below
Position: Histotechnician 2, 3rd Shift (Tues - Sat)

Overview

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest time points, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development.

Personalis is based in Fremont, California.

Summary:

Under the direction of the department supervisor, technical/clinical consultant, and laboratory director, the Histotechnician 2 will be responsible for processing FFPE specimens for microscopic evaluation to support our molecular diagnostics test offerings. Onsite:
Tuesday - Saturday, 8:00pm - 4:30am.

Responsibilities
  • Perform sectioning of tissue using a microtome and mounting on glass slides
  • Perform routine staining of tissue sections with automated and/or manual staining techniques
  • Perform automated and/or manual cover slipping of slides
  • Generate digital slide images for pathologist examination
  • Perform manual and automated macrodissection
  • Operate and perform instrument maintenance
  • Perform histology lab functions while following laboratory safety and quality policies
  • Comply with standard laboratory operating policies and procedures
  • Use of good documentation practices to record specimen data manually or in Laboratory Information Management Systems
  • Help meet TAT goals while maintaining high-quality productivity
  • Maintain clean and organized work areas within the laboratory
  • Report problems to the department supervisor/manager to ensure timely resolution
Requirements
  • Associate's degree in chemical/physical/biological science or completion of a NAACLS-accredited Histotechnology program;
    Bachelor s degree in a laboratory science curriculum preferred
  • Minimum of 3+ years experience working in a high-volume histology laboratory performing microtomy of various tissue types, H&E staining, and tissue embedding
  • HT or HTL certification from ASCP required
  • Experience working in IHC and digital imaging, tissue/tumor identification, and proficiency in reading pathology reports, a plus
  • Excellent attention to detail, organization, and time management skills
  • Ability to communicate effectively with excellent interpersonal skills
  • Physical demands include stooping, turning, bending, squatting, kneeling, and the ability to lift up to 25 lbs.
Compensation and benefits

The hiring range for this position is $40.00 to $50.00 per hour, which may factor in various geographic regions.
This shift is eligible for a shift differential pay bonus. The base pay actually offered will take into account internal equity and also may vary depending on the candidate s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Security

notice

Protecting Our Candidates:
At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from  email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Disclaimer



Note:

Some benefits mentioned are US-only and may vary in other countries. This text retains original language but has been reformatted for clarity and accessibility.

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