Senior Scientist - Critical Reagents

Position: Senior Scientist I - Critical Reagents
We are seeking a highly skilled and motivated Senior Scientist specializing with Biochemistry/Chemistry background to join B2S Critical Reagents Team Umbrella. The ideal candidate will play a key role in diligent design, generation, and characterization of critical reagents directly to the advancement of large molecule bioanalytical pipelines.

Position Summary :

The Senior Scientist I - Critical Reagents is responsible for the generation, characterization, and lifecycle management of custom critical reagents to support the development of robust, regulated bioanalytical assays for large-molecule biotherapeutics. Critical reagents include well-characterized polyclonal and monoclonal antibodies, recombinant proteins, conjugated proteins and peptides, gene therapy vectors, oligonucleotides, and critical reagent kits.

This position offers an exciting opportunity to lead and collaborate within a multidisciplinary scientific environment, contributing to innovation, assay robustness, and scientific excellence across the development lifecycle of large-molecule biotherapeutics.

Key Responsibilities.

• Serves as a Scientist/Principal Scientist for clients' projects.
• Performs a variety of protein conjugation chemistry, protein purification activities and downstream biochemical/bioanalytical and biophysical characterization methodologies.
• Able to design, execute, trouble shoot experiments associated with critical reagents generation and /or characterization with minimum supervision.
• Compiles scientific data (including analysis and technical writing) and able to present data in an intelligible format suitable for a professional audience.
• Able to train junior level scientists.
• Reports and treats data with prominent level of integrity and ethics.
• Complies with application able regulations (GXP); maintains proper records in accordance with standard operating procedures (SOPs) and policies; independently designs and performs scientific experiments with a pre-defined goal including developing new methodologies, protocols, and/or test procedures that contribute to core group research goals and reflect expert knowledge.
• Independently apply basic scientific principles, performs literature searches, attends scientific meetings, and keeps up to date on literature in the biotherapeutic bioanalysis field.
• Maintains laboratory equipment, as needed.
• Other duties as assigned

Competencies :

• Quality and Quantity - Demonstrates accuracy and thoroughness;
  Looks for ways to improve and promote quality;
  Applies feedback to improve performance;
  Monitors own work to ensure quality;
  Meets productivity standards;
  Completes work in timely manner;
  Strives to increase productivity;
  Works quickly but efficiently.
• Analytical - Synthesizes complex or diverse information;
  Collects and researches data;
  Uses intuition and experience to complement data;
  Designs workflows and procedures.
• Safety and Security - Observes safety and security procedures;
  Determines appropriate action beyond guidelines;
  Reports potentially unsafe conditions;
  Uses equipment and materials properly.
• Problem Solving - Identifies and resolves problems in a timely manner;
  Gathers and analyzes information skillfully;
  Develops alternative solutions;
  Works well in group problem solving situations;
  Uses reason even when dealing with emotional topics.
• Oral and Written Communication - Speaks clearly and persuasively in positive or negative situations;
  Listens and gets clarification;
  Responds well to questions;
  Demonstrates group presentation skills;
  Participates in meetings.

Requirements

Education

• Ph.D. degree in biochemistry, chemistry or related discipline with related experience in biology/chemistry techniques is required.
• M.S. degree in biochemistry, chemistry or a related discipline, 10+ years with related experience in biology/chemistry techniques is required.

Experience

• Hands-on experience with protein purification methodologies using various chromatography techniques.
• Proficiency in basic protein characterization techniques such as ELISA, SDS-PAGE, analytical chromatography techniques [E.g. SEC, NP/RP - HPLC, ion exchange methodologies]
• Optional Technical
  
  Skills:
  
  Experience or familiarity with…