Analytical Chemist

Yoh is hiring a QC Analytical Chemist for our El Segundo, CA client. In this role, you will be a hands-on technical contributor responsible for executing, troubleshooting, and overseeing HPLC-based analytical testing in support of OTC drug and cosmetic product release, stability, and validation activities. This position serves as the primary HPLC subject matter expert within Quality Control, ensuring data integrity, GMP compliance, and timely batch disposition while actively working at the bench.

The QC Analytical Chemist works under the general direction of the Quality Control Director.

• Industry: Cosmetics
• Location:
  
  El Segundo, CA
• Compensation: $85, Annually DOE
• Type:
  Direct Hire

• Independently perform HPLC testing of raw materials, in-process samples, finished OTC drug products, stability samples, investigational samples, validations, and studies.
• Prepare standards, samples, mobile phases, and reagents according to approved analytical methods.
• Execute system suitability testing, injections, and data processing with minimal supervision.
• Actively perform bench work while meeting QC turnaround times and release deadlines.
• Perform first- and second-level review of chromatographic data and calculations.
• Lead and support OOS, OOT, deviation, and laboratory investigation activities.
• Conduct root cause analysis and implement corrective and preventive actions (CAPAs).
• Defend analytical results during internal and external audits.
• Write, execute, and support method validation, verification, and transfer protocols and reports for OTC drug products.
• Write, execute, and support bulk hold studies, cleaning validation, and recovery study protocols and reports as required.
• Evaluate and implement USP and compendial methods applicable to OTC monographs.
• Troubleshoot analytical methods and instrument issues to minimize downtime.
• Operate, maintain, and troubleshoot HPLC systems.
• Perform routine instrument maintenance, column performance evaluations, and readiness checks.
• Maintain instrument logs, usage records, and calibration documentation.
• Interface with vendors and service providers for instrument service and qualification support.
• Ensure all QC activities comply with 21 CFR Parts 210/211, OTC monographs, USP/NF, and internal SOPs.
• Maintain accurate, contemporaneous laboratory documentation in compliance with ALCOA+ principles.
• Author and revise SOPs, analytical test methods, and protocols.
• Support FDA inspections and third-party audits for OTC drug and cosmetic operations.
• Provide technical guidance and on-the-job training to junior QC analysts.
• Support analyst qualification and method proficiency assessments.
• Serve as the QC analytical point of contact for Manufacturing and Quality Assurance.

• Bachelor’s degree in Chemistry, Pharmacy, Biology, or a related scientific discipline, or equivalent work experience.
• Minimum of 5 years of hands-on analytical chemistry experience in a GMP-regulated QC laboratory.
• Strong experience supporting OTC drug and/or cosmetic product testing.
• Demonstrated success in a high-throughput, release-driven QC environment.
• Experience with method validation, OOS investigations, and audit preparation and response.
• Experience supporting regulatory inspections, cGMP audits, and method or process validation.
• Strong working knowledge of FDA OTC regulations, USP/NF methods, and ICH stability guidelines.
• Demonstrated discretion in handling confidential and sensitive information.

• We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada.
• Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you.
• Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:
• Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
• Health Savings Account (HSA) (for employees working 20+ hours per week)
• Life…