PhD in Personalized hemodynamic modelling of carotid artery stenosis stroke prediction

• Are you fascinated by cardiovascular biomechanics and its application to medical decision support?
• Are you eager to be trained to develop multi-level thrombosis risk prediction models by integrating cell-, thrombus-, and organ-level insights?
• Are you passionate about being part of a prestigious MSCA doctoral network working on revolutionizing personalized medicine through cutting-edge in silico, in vitro, and in vivo technologies to understand, predict and treat thrombosis?

At the faculty of Biomedical Engineering at Eindhoven University of Technology, a PhD-position is available within the Thromborisk project, a Marie Sklodowska-Curie Actions (MSCA) Doctoral Network funded by the EU. The position is open for appointment during the course of , with a duration of 48 months hosted by TU/e, and includes secondments at the partner institutes within the consortium for a cumulative period of 12 months.

As a doctoral candidate (DC), you will be embedded in the Cardiovascular Biomechanics group, led by Prof. Huberts, which focuses on computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis, prognosis, and intervention. Within this collaborative environment, you will work closely with Maastricht University Medical Center, participate in secondments, and supervise BSc/MSc students on related projects.

Your main challenge will be to develop personalized in silico and in vitro hemodynamic models of the carotid artery bifurcation. These models will form the basis of a tool to evaluate the potential for carotid artery thrombus embolization, ultimately contributing to clinical trials aimed at predicting patient‑specific stroke risk.

This position offers the opportunity to contribute to research with high societal impact: improving stroke risk prediction and supporting personalized treatment strategies.

Thrombo Risk – European Doctoral Network From cells to systems:
Pioneering multi-level thrombosis risk prediction models consortium is funded by the European Union under Grant Agreement No. . It groups 10 hiring universities:
Eindhoven University of Technology (NL), University of Maastricht (NL), University of Amsterdam (NL), Catholic University Leuven (BE), Charité – Universitätsmedizin Berlin (DE), University College London (UK), Transsilvania University of Brasov (RO), SANO Centre for Computational Personalized Medicine (PL), University of Leeds (UK), and University of Bern (CH).

Thrombo Risk will develop an integrated platform to advance our understanding of thrombosis across biological scales, combining mechanobiology, biochemistry, pathophysiology, and computational modelling. For this inclusion to occur, each DC will develop through their research a unique contribution to the multi‑level thrombosis risk prediction framework, addressing specific aspects of thrombus formation, growth, rupture, and clinical impact. This hands‑on training is supplemented with several scientific professional courses and an immersive training program where the DCs can fine‑tune their skills for the jobs of tomorrow, while addressing the societal challenges of the Thrombo Risk program.