Senior Software Salesforce Engineer, Test; Menlo Park, CA or Durham, NC

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit

GRAIL is seeking a Senior Software Development Engineer in Test, Salesforce to join our Commercial Technology organization. In this role, you will be responsible for ensuring the quality, reliability, and compliance of our Salesforce ecosystem, which includes Sales Cloud, Service Cloud, Account Engagement, Marketing Cloud, and related enterprise integrations. You will play a critical role in supporting commercial and service workflows in a regulated healthcare environment by designing and implementing scalable automated testing frameworks and quality processes.

This is an opportunity to directly impact mission‑critical systems that enable early cancer detection  will collaborate closely with Salesforce Engineers, Product Managers, QA, and cross‑functional stakeholders to deliver high‑quality, compliant releases in alignment with SDLC and regulatory expectations.

Flexible - MPK or RTP (3 days in office)–– This is a hybrid role based in either Menlo Park, CA (moving to Sunnyvale, CA in Fall 2026) or Durham, NC. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on‑site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.

• Design, develop, and maintain scalable, reusable automated test frameworks across the Salesforce ecosystem (Sales Cloud, Service Cloud, Account Engagement, Marketing Cloud).
• Develop and maintain canonical test data sets to support comprehensive end‑to‑end testing scenarios.
• Build and integrate full‑stack automated test suites into CI/CD pipelines.
• Create end‑to‑end test scenarios across functional and non‑functional requirements, including integration testing with internal and external systems.
• Test Salesforce integrations including asynchronous event‑driven and synchronous real‑time API interactions.
• Collaborate with Developers, Salesforce Engineers, and Product Managers to ensure requirements are traceable and adequately validated.
• Triage defects, reproduce issues, perform root cause analysis, and partner cross‑functionally to resolve defects efficiently.
• Ensure testing practices and documentation align with regulatory requirements (e.g., GxP, FDA expectations).
• Contribute to continuous improvement of testing methodologies, automation coverage, and SDLC best practices.
• Document, track, and elevate issues using JIRA and related tools while maintaining strong stakeholder communication.

These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

• Bachelor’s degree in Computer Science, Information Systems, or related field, or equivalent experience.
• 5+ years of experience in software quality engineering or SDET roles.
• 3+ years of experience testing Salesforce applications with strong functional knowledge of Salesforce Platform.
• 3+ years of experience building automated test frameworks and integrating them into CI/CD pipelines.
• Experience with Salesforce testing frameworks including Apex testing, Jest, and Flow testing.
• Experience testing Salesforce integrations including asynchronous event‑driven architectures and synchronous…