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Postdoctoral Fellow or Staff Scientist - Protein Chemistry, Crystallography and Structure Deter

Job in Duarte, Los Angeles County, California, 91010, USA
Listing for: City of Hope
Full Time position
Listed on 2025-12-02
Job specializations:
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 38.67 USD Hourly USD 38.67 HOUR
Job Description & How to Apply Below
Position: Postdoctoral Fellow or Staff Scientist - Protein Chemistry, Crystallography and Structure Deter[...]
Thank you for your interest. Please note, this posting is for ongoing and future positions.

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated faculty and staff are driven by a mission: contribute to innovative approaches in predicting, preventing, and curing diseases through cutting-edge research.

The John Williams research lab at City of Hope is seeking a Postdoctoral Fellow or a Staff Scientist to join an innovative team. Our research focuses on structural and biophysical methods to identify sources of energy additivity and multivalency in macromolecular complexes, using these properties to develop new tools and therapeutics.

As a successful candidate, you will:
  • Determine the structure of modified antibodies with immune receptors
  • Apply yeast display to stabilize and deimmunize proteases
  • Create additional antibody variants to maximize therapeutic activity in a clinical setting
  • Qualifications

    Your qualifications should include:

    • Ph.D. in chemistry, biochemistry, structural biology, biophysics, or a related discipline
    • Knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection, structure determination), biochemistry (enzyme kinetics), and biophysics (Surface Plasmon Resonance, Isothermal Titration Calorimetry)
    Additional Information:
    • To apply, send your CV or resume to Dr. John Williams at jcwilliams
    • Candidates will be assessed based on relevant experience
    • Postdoctoral Fellow - Pay Rate: $34.00 - $37.54
    • Staff Scientist - Pay Rate: $38.67 - $123.37

    City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity, and inclusion, .

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