Senior Principal Scientist - Drug Metabolism and Pharmacokinetics; m​/f​/d

At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us.

If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.

As a leader in the design, execution, and analysis of in vitro ADME assays, you will evaluate the biotransformation of new drug candidates. You will provide scientific expertise in Drug Metabolism and Pharmacokinetics (DMPK) to project teams, guiding them on ADME-related issues throughout the drug discovery and development process. Your role will involve collaboration with cross‑functional teams to integrate DMPK strategies into project plans, ensuring alignment with overall drug optimization goals.

You will also prepare and present scientific findings to stakeholders, contributing to strategic decision‑making processes.

• Lead matrix teams within a laboratory context
• Provide scientific expertise in DMPK to project teams, offering guidance on ADME-related issues throughout the drug discovery and development process
• Collaborate with cross‑functional teams to integrate DMPK strategies into project plans, ensuring alignment with overall drug optimization goals
• Prepare and present scientific findings to stakeholders, contributing to strategic decision‑making processes
• Maintain a comprehensive understanding of biotransformation processes and their implications for drug metabolism and pharmacokinetics; work with colleagues to enhance data collection and reporting practices, ensuring robust support for scientific research and development of new drug candidates
• Drive innovation in assay development methodologies to improve the understanding of biotransformation and new molecules
• Actively participate in project meetings, providing insights on DMPK topics and influencing project direction based on scientific evidence
• Mentor junior scientists and contribute to the development of best practices in assay development and biotransformation studies

• Ph.D. in Biology, Chemistry, Pharmaceutical Sciences, or a related field
• Extensive experience in DMPK, with a focus on assay development in biotransformation, particularly metabolite identification from in vitro and in vivo studies; long‑term experience in the pharmaceutical industry preferred
• Strong experience in high‑resolution mass spectrometry and analytics
• A solid background in drug discovery and development processes as well as scientific rigor, efficiency, and a strong organizational skill set
• Strong communication and interpersonal skills, capable of working collaboratively across departments
• Ability to manage multiple projects and priorities in a fast‑paced environment
• Knowledge of relevant methodologies and technologies for biotransformation studies
• English fluently; verbally and in writing

Our benefits package is flexible, appreciative, and tailored to your lifestyle, because:
What matters to you, matters to us!

• We ensure your financial stability through a competitive compensation package, consisting of an attractive base pay and our annual bonus.
• Whether it’s hybrid work models or part‑time arrangements:
  Whenever it is possible, you will have the flexibility to work how, when and where it is best for you.
• Your family is a top priority. We offer loving company daycare centers at multiple locations, support in finding childcare, time off for the care of elderly or dependent family members, summer camps for children, and much more.
• We support your professional growth by providing access to learning and development opportunities, training programs through the Bayer Learning Academy, development dialogues, as well as coaching and mentoring programs.
• We promote health awareness and opportunities for self‑care through various measures, such as free health checks with the company doctor and our health platform #machtfit.
• We embrace diversity by providing an inclusive work environment in which you are welcomed, supported, and encouraged to bring your whole self to work.

Ever feel burnt out by bureaucracy? Us too. That’s why we’re changing the way we work – for higher productivity, faster innovation, and better results. Learn more about what DSO will mean for you in your new role.

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