Senior Information Security Engineer – Endpoint Engineer
Listed on 2026-03-11
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IT/Tech
Cybersecurity, Systems Engineer
Job Description
Join a world‑class academic healthcare system, UChicago Medicine, as a Senior Information Security Engineer in our Information Security department. This is a remote, work‑from‑home opportunity, and you may be based outside of the greater Chicagoland area.
This role will be that of a Senior Information Security Engineer. You will lead our effort in enhancing and maturing our defensible architecture across our network and cloud solutions. Besides network‑related tasks, you will also assist Incident Response as needed and will produce written documentation to improve processes and procedures. Additionally, you will primarily be responsible for creating Standard Operating Procedures for our SOC operations related to all Network Security solutions implemented by you.
Under general direction of Information Security leadership, you will implement and operate security controls to minimize risk to physical and logical assets of the University of Chicago Medical Center and ensure the confidentiality and integrity of UCMC sensitive information. The Information Security Engineer will assist with the core security activities of UCMC and lead many enhancement projects, including but not limited to design and implementation of enterprise network security systems, security operations, threat analysis, log and event management, and network monitoring.
EssentialJob Functions
- Primary subject‑matter expert for all Endpoint Security related functions.
- Deploy, configure, and manage Endpoint Detection and Response (EDR) solutions (e.g., Crowd Strike, Microsoft Defender ATP, Sentinel One).
- Design and maintain endpoint security architectures (Windows, Mac, Linux).
- Assist other security engineering and consulting needs as they arise.
- Develop project plans and manage project teams for security related projects.
- Provide communications, including status reporting, risk management, escalation of issues, and ensure projects are delivered on budget, on schedule, and within scope.
- Other duties as assigned.
- BS or BA degree in Computer Science or other IT related field, or a combination of education and work experience.
- 8 years of Information Security experience, required, with at least 3 years in a Senior or Lead Engineering role.
- 5 years’ experience maintaining and designing Defense‑in‑Depth strategies for complex network architectures.
- Proficiency in deploying, configuring, and troubleshooting EDR and AV solutions.
- Effective written and verbal communication skills.
- Good working knowledge of the Plan, Build, Run model within an IT environment.
- Some scripting or programming skills (PERL, Python, Power Shell, etc.) preferred as needed.
- Expert understanding of TCP/IP (OSI Layers 1–4) and Internet and Intranet technologies (OSI Layers 5–7).
- Good knowledge of Windows and Linux Operating Systems.
- Good knowledge of vulnerability management, risk analysis, and forensics preferred.
- Experience with HIPAA, NIST, FERPA, and SOX preferred.
- Job Type/FTE:
Full‑time - Shift: Days
- Location:
Remote - Department:
Information Security - CBA Code:
Non‑Union
We’ve been at the forefront of medicine since 1899. We provide superior healthcare with compassion, always mindful that each patient is a person, an individual. To accomplish this, we need employees with passion, talent and commitment … with patients and with each other. We’re in this together: working to advance medical innovation, serve the health needs of the community, and move our collective knowledge forward.
If you’d like to add enriching human life to your profile, UChicago Medicine is for you. Here at the forefront, we’re doing work that really matters. Join us. Bring your passion.
UChicago Medicine is growing; discover how you can be a part of this pursuit of excellence at: UChicago Medicine Career Opportunities.
UChicago Medicine is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, ethnicity, ancestry, sex, sexual orientation, gender identity, marital status, civil union status, parental status, religion, national origin, age, disability, veteran status and other legally protected characteristics.
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