Principal NPI Engineer

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn

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As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Supply Chain Engineering

Job Sub Function:

Process Engineering

Job Category:

Scientific/Technology

All Job Posting Locations:

Danvers, Massachusetts, United States of America

Job Description:

We are searching for the best talent for Principal NPI Engineer.

Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized treatments.

Are you passionate about improving and expanding the possibilities of Cardiovascular? Ready to join a team that's reimagining how we heal? Our Cardiovascular team develops leading solutions for heart recovery, electrophysiology, and stroke. You will join a proud heritage of continually elevating standards of care for stroke, heart failure and atrial fibrillation (AFib) patients.

Your unique talents will help patients on their journey to wellness. Learn more at

Key Responsibilities

Technical Leadership & Strategy

* Serve as the technical expert and decision-maker for supplier and process engineering strategy across major NPI programs.

* Act as a key technical leader in the process development and engineering space. Leading initiatives to support process and SOP improvement while upskilling existing team members, and supporting the implementation of a structured approach to process development.

* Lead efforts to optimize new and existing manufacturing processes through the application of scientific and data-driven methodologies, ensuring efficiency, scalability, and compliance with regulatory standards.

* :
Implement and promote the use of data analytics to drive decision-making processes, leveraging statistical methods and process monitoring tools.

* Establish best practices, process standards, and validation frameworks that elevate organizational capability.

* Drive long‑term manufacturing and supplier technology roadmaps that support product innovation and business growth.

Supplier & Process Industrialization

* Lead industrialization strategies for highly complex, novel, or critical manufacturing processes at internal sites and supplier locations.

* Oversee advanced development of high‑risk processes and ensure design concepts align with manufacturability, yield, reliability, and scalability.

* Assess and develop supplier capabilities, including technology readiness, process robustness, and capacity planning.

Influence on Product Architecture

* Drive early and deep engagement with R&D to shape product design through advanced DFX, cost modeling, and capability analysis.

* Influence design decisions to mitigate risk, enhance robustness, and accelerate commercialization.

* Serve as the technical voice representing manufacturing, scalability, and supplier capability in design reviews and program governance.

Process Validation & Quality Compliance

* Define validation approaches for complex or novel processes, ensuring full alignment with FDA, ISO 13485, and internal quality systems.

* Challenge and elevate risk management practices (PFMEA, control plans, capability studies).

* Provide technical oversight for supplier PPAP, tooling qualifications, and readiness assessments.

Program Leadership

* Lead cross‑functional teams through readiness reviews, risk closure, and launch decision gates.

* Anticipate risks early, develop mitigation plans, and guide resolution of technical issues.

* Communicate technical…