Research Associate - Molecular Medicine & Therapeutics

Overview

The Chandler Laboratory is seeking a highly motivated and skilled Research Associate to investigate the molecular mechanisms of alternative splicing in cancer, with a particular focus on the p53 tumor suppressor pathway and cell signaling growth pathways. The successful candidate will contribute to cutting-edge research exploring the links between DNA damage, RNA processing, and tumorigenesis, using a combination of cell culture, in vitro splicing assays, and genetically engineered mouse models.

The Research Associate will participate in planning, design, execution, and management of research projects in a foundational (basic) biological/health science research laboratory.

• Investigating the regulation of alternative splicing in response to genotoxic stress, hypoxia and other tumor stressors.
• Characterizing models of splicing regulation and their implications for post-transcriptional regulation.
• Developing and testing therapeutic tools to modulate splicing in cancer-related genes.
• Utilizing novel delivery systems for RNA therapeutics in vivo.

Minimum Education Required
Bachelor’s Level Degree or equivalent combination of education and experience.

Required Qualifications
Bachelor's Degree or equivalent experience required; 3 years of relevant experience required with Associate's Degree, or 1 year of relevant experience required with Bachelor's Degree. MS degree in a relevant scientific discipline is a plus, experience with RNA processing and splicing assays is highly desirable as is familiarity with animal models (mouse/rat):
Ability to translate, adapt and apply academic and/or practical knowledge in the conduct of biological/health science research is required. Experience in a biological/health science research capacity is preferred.

Function:
Research and Scholarship

Sub Function:
Research

Career Band: S

Career Level:

S1

Location
:
Pelotonia Research Center (1040)

Position Type
:
Regular

Scheduled Hours
: 40

Shift
:
First Shift

Conditions
:
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.

Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. The university is an equal opportunity employer, including veterans and disability. For answers to additional questions please review the frequently asked questions. The status of submitted applications can be reviewed in the Candidate Home section of this site.