Research Associate, Clinical Research, Research Scientist

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We are seeking a highly motivated Research Associate to support experimental research in hematology, leukemia biology, and immuno-oncology. The ideal candidate will have hands-on experience with bone marrow-derived cells, hematopoietic and immune assays, and high-dimensional flow cytometry, along with a strong interest in translational cancer research and learning new technologies.

This position will contribute to studies focused on hematopoietic differentiation, leukemia-immune interactions, and immune-based therapeutic strategies, including CAR-T cell approaches.

• Participate in the planning, design, and execution of research projects related to hematopoiesis, leukemia, and tumor immunology, including the development and implementation of experimental goals and study objectives.
• Execute and manage research projects using molecular and cellular biology techniques, including DNA/RNA extraction, RT-PCR, cloning, bacterial transformation, plasmid isolation, transfection, viral transduction of immune and hematopoietic cells, and CRISPR-Cas9 gene editing.
• Perform bone marrow– and blood-based assays, including collection, processing, enrichment, and analysis of hematopoietic stem and progenitor cells, leukemic cells, and immune populations.
• Conduct high-dimensional flow cytometry experiments, including panel design, staining, acquisition, compensation, and basic downstream analysis, with an emphasis on hematopoietic and immune phenotyping.
• Assist with T cell-based functional assays, CAR-T cell generation, and immune effector testing in hematologic and solid tumor models.
• Participate in murine models of leukemia and cancer, including injections, monitoring, bone marrow and tissue collection, and downstream analyses.
• Perform immunohistochemistry, Western blotting, tissue culture, and related assays to support mechanistic studies.
• Collect, analyze, and interpret experimental data; assist in developing and optimizing new or revised methodologies relevant to hematopoietic and immune research.
• Perform critical analysis of the scientific literature related to hematology, leukemia, and immuno-oncology projects.
• Contribute to the preparation of manuscripts, figures, grant applications, and presentations for national meetings and workshops.
• Maintain accurate records of protocols, results, and inventories; support data organization and presentation.
• Assist with laboratory operations, including inventory management, procurement of supplies, routine maintenance, and coordination of equipment servicing.
• Train and support research staff as needed and participate actively in lab meetings, troubleshooting, and protocol optimization.
• Perform additional duties as assigned.

• Bachelor’s degree in Biology, Immunology, Molecular Biology, or a related field.
• 1 year of prior experience in a research laboratory performing hematopoietic, leukemia, or immune-based assays, including molecular biology and/or cellular immunology techniques.
• Comfort working with human and murine blood and bone marrow samples and biosafety level 2 materials.
• Successful completion of a background check.

• Experience with bone marrow-derived cells, hematopoietic stem/progenitor cell assays, or leukemia models.
• Proficiency in high-dimensional flow cytometry (≥20 colors), including panel design, compensation, and gating strategies.
• Hands-on experience with T cell transduction, CAR constructs, or gene-editing approaches.
• Prior experience with murine models of leukemia or immune response.
• Strong organizational skills, attention to detail, and willingness to learn and adapt to evolving experimental needs.

• Detail-oriented, with careful adherence to protocols.
• Strong willingness to learn new techniques and adapt to unfamiliar workflows.
• Reliable, organized, and able to work both independently and collaboratively. Positive responsiveness to feedback.
• Positive attitude, scientific curiosity, and motivation to grow in a translational research environment.

Role Context

Function:
Research and…