Senior Associate Scientist, MS&T

Forge Your Future With Us

At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you’re driven by purpose and excited to make a tangible impact, this is where your journey begins.

Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won’t just watch innovation happen — you’ll be part of it. Whether you’re scaling AAV manufacturing, collaborating on cutting‑edge therapies, or supporting complex technical projects, you’ll play a key role in bringing hope to patients with genetic diseases.

We are hardworking
, showing up each day with determination and grit. We are open
, creating a space where ideas flow freely and every voice is valued. We are purpose‑driven
, with every task directly tied to changing lives. And we are engaged
, energized by the challenges we face and the milestones we achieve together.

At Forge, your growth matters. We’re committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands‑on learning, and opportunities for advancement. Our people are our greatest investment, and we’re proud to see team members grow with us.

If you’re ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself.

As an Associate Scientist II Senior Associate Scientist, MS&T, you will play a key role in developing, optimizing, and supporting gene therapy manufacturing processes within the Manufacturing Science and Technology (MS&T) department. This multidisciplinary role collaborates closely with process development, manufacturing, quality, validation, facilities and engineering, and regulatory teams to ensure upstream, downstream, fill‑finish, buffer preparation, and support‑function processes are scalable, robust, and aligned with regulatory expectations.

As a reliable independent contributor, you will execute moderately complex, recurring assignments, adapting established procedures to varied situations and identifying refinements that enhance consistency and performance. You will help identify minor process gaps, support continuous improvement initiatives, and strengthen overall operational reliability, while also training peers on foundational tasks and occasionally influencing adjacent functions. Through this work, you will contribute to day‑to‑day operational excellence, team deadlines, audit readiness, and quality outcomes, playing a meaningful role in the organization’s broader success.

• Serve as a technical contributor during technology transfer activities from Process Development or clients into GMP Manufacturing, including defining critical quality attributes, key process parameters, and conditions essential for compliant manufacturing under cGMPs.
• Lead the development, review, and maintenance of key documentation such as manufacturing batch records, production plans, bills of materials and SOPs.
• Perform process monitoring by collecting, analyzing, and summarizing manufacturing data; prepare campaign summary reports and provide insights that strengthen process understanding and operational decision‑making.
• Support GMP execution of new processes and act as a Subject Matter Expert (SME) for change controls, deviation investigations, and CAPAs.
• Track progress of routine manufacturing and technology transfer activities, provide timely updates, and proactively identify operational risks and mitigation strategies.
• Build strong working relationships with internal teams and external clients, communicating responsibilities, expectations, and technical information clearly and respectfully to ensure GMP readiness and provide technical support throughout production campaigns.
• Train peers on foundational tasks and demonstrate increasing independence in…