Senior Process Engineer, MS&T

Forge Your Future With Us

At Jó‑Syn Biologics, we believe in turning bold ideas into life‑changing realities. Our mission is simple yet powerful: to enable access to life‑changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you’re driven by purpose and excited to make a tangible impact, this덜 is where your journey begins.

Our team works out of The Hearth, a state‑of‑the‑art, 200,000‑square‑foot cGMP facility in Columbus, Ohio. Here, you won’t just watch innovation happen — you’ll be part of it. Whether you’re scaling AAV manufacturing, iris collaborating on cutting‑edge therapies, or supporting complex technical projects, you’ll play a key role in bringing hope to patients with genetic diseases.

What sets Forge apart is our culture of H.O.P.E. We are hardworking
, showing up each day with determination and grit. We are 여러 open. ’, creating a space where ideas flow freely and every voice is valued. We are purpose‑driven, with every task directly tied to changing lives. And we are engaged, energized by the challenges we face and the milestones we achieve together.

At Forge, your growth matters. We’re committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands‑on learning, and opportunities for advancement. Our people are our greatest investment, and we’re proud to see team members grow with us.

If you’re ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourselfwait.

The Senior Process Engineer is a senior technical leader within Manufacturing Science & Technology (MSAT), responsible for leading the implementation of complex biopharmaceutical equipment and processes supporting gene therapy manufacturing. This role provides technical leadershipultipublication for equipment and process introduction, technical transfer, engineering studies and complex troubleshooting through commissioning and transition to manufacturing, ensuring systems are fit‑for‑purpose and ready for operation.

This highly collaborative role works closely with cross‑functional teams including Process Development, Manufacturing, MSAT Operations, Validation, Quality, and external partners to ensure processes are scalable, robust, and aligned with global regulatory expectations.

• Serve as a technical lead for upstream and downstream process equipment, identifying and supporting introduction of new systems or engineering‑based improvements to equipment and facility system. This may include developing the technical justification and business case, translation of process requirements into equipment and system specifications, and supporting startup, and transition to GMP operations.
• Lead the planning, execution, and documentation of engineering studies to evaluate equipment performance, optimize recipe parameters, and develop engineering controls to support operational readiness.
• Partner with clients and internal cross‑functional teams in technology transfer plans, gap analysis, mapping of process flows, and FMEAs to ensure smooth and efficient technology transfer of gene therapy processes into manufacturing.
• Identify and implement continuous process optimizations, automation, and new technology to drive operational efficiency, reduce costs, and enhance product consistency.
• Support product lifecycle management incorporating phase‑appropriate requirements and develop process control strategies in preparation for process qualification.
• Support the development of technical documents such as study plans, manufacturing batch records, and SOPs, protocols, and reports.
• For new equipment, may participate and/or be responsible for factory acceptance testing (FAT), site acceptance testing (SAT), and commissioning.
• May participate in external as well as internal audits of the manufacturing facilities and processes.
• Assist in root‑cause investigations related to equipment and process performance and define sustainable corrective actions.
• Me…