Director, Onyx Enablement

Overview

Site Name: USA - Pennsylvania - Upper Providence, London The Stanley Building, USA - Massachusetts - Boston

Posted Date: Feb 2 2026

Director, Onyx Enablement

Business Introduction

At GSK, we want to supercharge our data capability to better understand our patients and accelerate our ability to discover vaccines and medicines. The Onyx Research Data Tech organization represents a major investment by GSK R&D and Digital & Tech, designed to deliver a step-change in our ability to leverage data, knowledge, and prediction to find new medicines. We are a full-stack shop consisting of product and tech delivery leadership, application and data engineering, infrastructure and Dev Ops, data / metadata / knowledge platforms, and AI/ML and analysis platforms, all geared toward:

• Building a next-generation, metadata- and automation-driven data experience for GSK’s scientists, engineers, and decision-makers, increasing productivity and reducing time spent on “data mechanics”
• Providing best-in-class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top-tier talent
• Aggressively engineering our data at scale, as one unified asset, to unlock the value of our unique collection of data and predictions in real-time
• Building data and prediction powered ways of working that accelerate GSK Research team’s ability to find new drugs and vaccines

We are looking for a Director, Onyx Enablement who will report to the Senior Director, Onyx Portfolio Management in a Chief-of-Staff capacity to enable operational discipline within the Onyx organization. This role is for a credible leader who is expected to build strong relationships with the Onyx Engineering, Product, Program, and Quality leads, R&D stakeholders, and Enterprise partners such as Recruitment, Procurement, Finance, Compliance, RD&DT Portfolio, Real Estate & Facilities, and others.

An excellent candidate should combine their strong operational leadership with exceptional cross-functional coordination skills, and be capable of building and running the core operational backbone of a complex engineering organization. This individual should have deep experience in procurement and vendor management, financial planning and forecasting, recruiting operations, and facilities coordination, with a demonstrated ability to establish scalable processes and governance structures.

They must excel at navigating senior stakeholders, managing organizational cadences, and translating strategic objectives into actionable operational plans. The ideal candidate brings a track record of driving clarity, predictability, and efficiency across diverse teams, supported by strong analytical skills and a disciplined, metrics-driven approach to organizational performance.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Develop and manage a comprehensive enablement and operational framework for Onyx, ensuring it is consistently applied across all Onyx teams.
• Partner with Procurement to drive procurement operations, including vendor selection, procurement strategy, contract execution, contract lifecycle management, and vendor performance tracking and reporting.
• Partner with Recruiting to manage hiring pipelines, coordinate interview logistics, accelerate onboarding, and ensure staffing plans align with organizational needs.
• Collaborate closely with Tech and R&D Finance to manage budgets, track and forecast spend, provide financial visibility, and ensure alignment to annual and quarterly budget targets (both OPEX and CAPEX).
• Coordinate with Real Estate and Facilities to manage Onyx’s physical office footprint, including space allocation, operational readiness, and ongoing site support.
• Serve as the primary liaison to the central RDDT Portfolio team, managing intake, routing, prioritization, and follow-up on organizational requests.
• Lead and orchestrate organization-wide cadences and governance, including Townhalls, quarterly business reviews, stakeholder updates, and cross-functional planning cycles.
• Establish and track…