Vice President, Medicine Development Leader
Listed on 2026-02-06
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Management
Healthcare Management
Vice President, Medicine Development Leader (MDL) – Renal Medicine, GSK
As the single point of accountability for a renal medicine from Proof of Clinical Concept (PoC) to approval in major markets, you will define the strategic vision and operational plan for the medicine and build a matrixed Medicine Development Team (MDT) to deliver the asset worldwide. You report to the SVP & Head Advanced Pipeline Unit – Respiratory, Immunology and Inflammation Research Unit.
Locations: On‑site office presence (minimum two days a week) in GSK US sites (PA or MA) or UK sites (London – New Oxford Street or Stevenage).
Location:
USA – Massachusetts – Waltham, GSK HQ, UK – Hertfordshire – Stevenage, USA – Pennsylvania – Upper Providence
About RIIRU: The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic evidence of causal roles. Core therapeutic areas include respiratory, hepatology, nephrology, neurodegeneration and rheumatology. RIIRU focuses on target identification, asset development, and trials through to approval, leveraging external and internal partnerships.
Key Responsibilities- Serve as the single point of accountability in GSK for all aspects of the medicine across global markets from PoC to approval.
- Collaborate with Early Development Lead (EDL) and Medicine Commercial Lead (MCL) to ensure a smooth transition from PoC to approval in the first major markets.
- Provide post‑approval support to the Medicine Commercial Team in major markets, ensuring optimal registration, Post‑Marketing Requirements (PMRs), and life‑cycle management (LCM).
- Select and lead MDT members, owning performance and partnering with line managers to drive high performance.
- Work with Pipeline Project Manager (PPM) to energize and motivate the MDT for operational delivery, including acceleration and risk‑tolerant options.
- Partner with R&D Business Development to plan prospective in‑licensed assets, integrating CMC risk mitigation, regulatory planning, and clinical feasibility.
- Lead the cross‑functional MDT to:
- Establish a compelling vision and Target Medicine Profile (TMP) aligned with GSK’s strategy and competitive landscape.
- Deliver differentiated medicines of value for patients, stakeholders and markets through evidence packages supporting regulatory approval, market access, and product lifecycle.
- Prioritize and maximize development options, including multiple indications.
- Partner with Global Medical Lead (GML) and MCL to develop indication expansion and LCM plans.
- Make clear evidence‑based go/no‑go/accelerate decisions and identify inflection points based on results.
- Ensure excellence in governance, oversight of clinical studies, patient safety, pharmacovigilance, scientific engagement, and promotional practices.
- Enhance patient focus by integrating the voice of the patient into development plans.
- Increase visibility within external communities to bring unmet medical needs to patients.
- Embed core processes: cost efficiency, new technology adoption, risk identification & management, policy compliance.
- Promote organizational reputation and drive asset value through stakeholder engagement.
- Ensure quality & compliance oversight in line with R&D expectations, ensuring data and science integrity.
- Act as the asset’s spokesperson to Senior Management, boards, governance committees, and external advisory committees.
- Deliver and manage the asset resourcing plan (people & finances), working closely with PPM and Finance Partner to maintain budget variance.
- Advanced degree (MD, PhD, Pharm
D, MBA, MS). - Drug development expertise in the global pharma/biotech industry.
- Filing experience with BLA/NDA/MAA submissions as a core responsibility.
- Experience across the entire drug development lifecycle (discovery to commercial).
- Experience in late‑stage development, clinical trial management, post‑approval studies, regulatory and manufacturing compliance.
- Experience leading teams in a complex, matrixed, global organization with high accountability.
- Experience working with regulators and regulatory requirements across global geographies.
- Experience developing pre‑ and…
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