Senior Global Medical Director

Site Name: USA - Pennsylvania - Upper Providence, Switzerland - Zug

Posted Date: Jan 15 2026

The Senior Global Medical Director role is a unique opportunity for an experienced, innovative, and proactive medical professional to facilitate the understanding of the value of our medicines and vaccines, the science behind them and the public impact they can offer. This is accomplished by developing and overseeing implementation of the global medical scientific strategic plan to generate insights, shape optimal care through scientific dialogue and education and delivering impact by generating and communicating the evidence and delivering solutions to close the gaps.

The Senior Global Medical Director, Gastrointestinal Stromal Tumors will work in a thriving team of medical business leaders where people will be inspired to drive towards achieving our goals of getting Ahead of Disease Together and positively impacting patient and population health outcomes globally.

• Development and timely execution of practice changing Global Medical Affairs Plans (MAP) and Integrated Evidence plans (IEP) in partnership with key stakeholders through the GMAT and IET.
• Thinks globally, while deeply understands priority LOC (Local Operating Company) needs and success measures. This is accomplished through extensive partnership and collaboration with LOC teams to understand landscape, market value drivers, unmet medical needs and timelines for deliverables required for their success.
• Drives alignment across the internal ecosystem and with external partners to deliver Medical Plans that prioritize external impact above all else on time and on budget.
• Leveraging insights and learnings, designs and oversees execution of GMA-sponsored clinical trials, and inputs into externally sponsored and clinical development research to optimize the positive impact for patients.
• Drives excellence in scientific engagement by developing and implementing a strategy a strong collaborative network of global external experts (HCPs, patients, payors and regulators) to be engaged in advice seeking activities and appropriate initiatives to advance clinical care and patient outcomes in partnership with the LOC Medical teams where those experts reside.
• Ensures team members and colleagues have a robust knowledge of the relevant and emerging clinical evidence, by overseeing the creation and delivery of high-quality scientific materials for both internal and external use as well as implementing a global training and competency framework.
• Partner with Global Product Strategy, Market Access, and core country teams to deliver evidence plans that meet the robustness of external communication needs. Support/advise teams on core claims and material review.
• Ensure appropriate medical governance oversight including management of product-related issues with potential impact on patient safety and of risk assessment and mitigation plan associated with deliverables/strategies.
• Development of deep subject matter expertise on the product and therapy area as well as the ability to drive proactive strategic planning.
• Drive a culture and delivery mindset of future ready innovation which supports faster and specific solutions for patients.

This role is hybrid, based in the United States. You will work regularly from a GSK office and have flexibility to work remotely. You will join a collaborative team that values curiosity, practical impact and clear communication. This role offers the chance to grow your influence, shape global medical approaches, and make a meaningful difference for patients.

• MD/MBBS/Pharm
  
  D or PhD in clinical / scientific discipline related to oncology.
• Considerable experience in Medical Affairs including strategic roles in LOCs (including the US) and in global teams supporting pre/peri launch phases of assets.
• People leadership experience at the global or LOC level.
• Experience prioritizing and managing multiple projects, budgets, and interactions simultaneously.
• Strong experience in collaborative team environment, as the role involves interface with a wide range of stakeholders internally and externally.

• Strong interpersonal, verbal, and written communication skills in English.
• Previous clinical or scientific experience in Oncology and/or GIST will be an added benefit.
• Robust understanding of internal and external codes of practice and regulations (certification where applicable).
• Demonstrated matrix leadership in previous roles with ability to build strong networks, manage complexity and cultural diversity.
• Experience in medical support for briefing documents for regulatory interactions and payor dossiers.
• General understanding of statistics, safety, regulatory requirements.
• Demonstrated experience with developing global or local medical strategies and asset launches, especially within a priority market.
• Skilled at simultaneous consideration of scientific…