Postdoctoral Research Fellow; Danzer Mechanism of Epilepsy

Dr. STeve Danzer has an immediate opening for a motivated postdoctoral research fellow. We are exploring the role of disrupted mTOR signaling in mediating the aberrant integration of abnormal neurons in the hippocampus. Mutations in mTOR signaling pathway genes, such as PTEN, TSC1 and TSC2, cause epilepsy, autism and cognitive dysfunction in humans. Ongoing research in the lab is aimed at understanding how disrupted mTOR signaling promotes the aberrant rewiring of hippocampal neurons, and whether modulating this pathway can be used to prevent and treat epilepsy.

• Develop the skills and knowledge (critical thinking and analysis of data, devising specific aims, long‑term project planning and experimental design) to become an independent scientist
• Design, execute, and record laboratory experiments, and analyze data, which may affect decisions regarding future patient care.
• Research and improve current methods and evaluate innovative techniques. Protocol and assay accuracy by conducting regular quality and reproducibility checks. Implement this knowledge in the Division/Department. Troubleshoot and correct erroneous results or problems with laboratory equipment.
• Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis.
• Present research at laboratory meetings, journal clubs, seminars, and meetings. Develop skills to critically review and discuss data being presented.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
• Progressively increasing responsibilities with mentorship of research staff and fiscal administration.
• Maintain currency in field through continuing education, literature, and seminars. Be an active participant in the process through intellectual discussions with PI and other faculty, trainees and research staff. Solicit feedback on career trajectory from PI, mentoring committee and others who can provide coaching and insight.
• Attend required Cincinnati Children’s training sessions and ensure regulatory compliance with all institutional (i.e. Infection Control, ORCRA and others as applicable) policies and procedures.
• Perform other duties as assigned.

• PhD/MD or equivalent

• Primary
  
  Location:
  
  S
• Schedule:
  
  Full time
• Shift: Day (United States of America)
• Department:
  Anesthesia
• Employee Status:
  Regular
• FTE: 1
• Weekly
  
  Hours:
  
  40

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability