Post Doc Fellow, Zhang Lab, UC College of Medicine, Department of Cancer Biology

Current UC employees must apply internally via Success Factors

Founded in 1819, the University of Cincinnati ranks among the nation?s best urban public research universities. Home to 53,235 students, nearly 12,000 faculty and staff and 350,000+ living alumni, UC combines a Top 35 public research university with a physical setting The New York Times has called ?the most ambitious campus design program in the country.?

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UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service. We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC?s success.

Job Overview

As one of the oldest medical schools in the country, the UC College of Medicine has a reputation for training best-in-classhealthcareprofessionals and developing cutting-edge procedures and research that improve the health and clinical care of patients.

The Department of Cancer Biology at the University of Cincinnati has an opening for a Postdoctoral Fellow supported by NCI R01 grants to study transcriptional and epigenetic gene regulation in breast cancer metastasis and therapeutic resistance. The Zhang laboratory ( (Use the "Apply for this Job" box below). ) currently focuses on elucidating the role and molecular mechanisms of gene- and tissue-specific transcriptional cofactors and small RNAsin liquid-liquid phase separation (LLPS) and the above processes [Estrogen Receptor and Breast Cancer ?

Celebrating the 60thAnniversary of the Discovery of ER (1sted, 2019, Springer Nature ),Cell Reports (2021) 34(10):108822, Dev Cell (2021) 56(3):341, Cancer Drug Resist (2022) 5(2): 498, Cancers (2024) 16(23):3992]. We are using a combination of biochemical, molecular, genomic, and mouse genetic (conditional knockout, mutant knocking, and over-expression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome the therapeutic resistance of human breast cancer.

Essential Functions

• Conduct research experiments in a particular field within the pre-determined research scope and methodology.
• Gather and analyze data and develop new ideas that promote current research.
• Prepare data summaries, reports, manuscripts and presentations of research results.
• Participate/assist in manuscript writing for publication in scientific journals and/or presentation; may assist in grant writing.
• Keep informed of developments in the field to maintain and enhance professional expertise.
• Lab maintenance, including equipment maintenance and ordering of supplies, as needed.
• May teach techniques to others, train, and mentor junior research staff.
• Engage in appropriate training and professional development opportunities.
• Play an active role in seeking career and research advice, both from the faculty supervisor and from other faculty members as well.
• Perform related duties based on departmental need. This job description can be changed at any time.

Required Education

Doctoral Degree in Molecular and Cellular Cancer Biology, Biochemistry, or a related field.

Additional Qualifications Considered

Prior experience with Cancer Biology, Animal Models, RNA Splicing or LLPS Biochemistry is ideal.

Physical Requirements/Work Environment

• Office environment/no specific unusual physical or environmental demands.

Compensation and Benefits

UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. ( UC Benefits Link ) Highlights include:

Comprehensive Tuition Remission

UC provides tuition remission for you and your eligible dependents, covering tuition costs for nearly all undergraduate and graduate programs offered by the university.

Robust Retirement Plans

As a UC employee, you won?t…