Principal Research Scientist II, Biologics Analytical Research and Development

Overview

Abb Vie s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. Abb Vie (NYSE: ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott.

Abb Vie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader to develop and market advanced therapies that address some of the world s most complex and serious diseases.

Abb Vie Biologics Analytical Research & Development (Biologics Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of Abb Vie s pharmaceutical products. Our scope includes Abb Vie s diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch.

We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance Abb Vie s pipeline of innovative medicines. Careers in Abb Vie Biologics Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.

The biologics characterization group develops state-of-the-art analytical techniques for in-depth characterization of therapeutic proteins and other novel biologic molecules using mass spectrometry and other advanced analytical techniques. We are looking for diverse candidates with strong scientific and leadership experience to join the Abb Vie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

• Develop and achieve discipline strategy in alignment with functional goals and key scientific objectives.
• Collaborates with experts integrating scientific objectives associated with development of new/improved products or technology.
• Advances scientific expertise within function. Proactively advises and shares knowledge and expert opinions with subordinates, peers, and senior management. Mentors and trains colleague and assesses current and emerging business challenges enabling functional goal achievement.
• Ensure quality and effectiveness of key results of major project plans through sound design, early risk assessments, and implementation of fallback strategies.
• Sources and identified emerging scientific trends from internal and external sources and assess relevance. Integrates trends into functional short-term objectives. Advances technology and direction within area of discipline.
• Applies imagination and innovation by creating, inventing, and implementing new or better approaches, alternatives and breakthrough ideas.
• Make significant contributions to project team and deliver results in a team-oriented setting and will work across scientific disciplines to drive programs through critical milestones.
• Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.

• PhD (with 8+ years  experience) in scientific discipline (e.g., Analytical Chemistry, Biochemistry, or Biology) with previous laboratory experience.
• Deep understanding of protein characterization by mass spectrometry (e.g., peptide mapping, intact mass analysis).
• Practical experience and strong knowledge of protein HPLC (e.g., SEC, IEX, HIC), capillary electrophoresis, and other separation techniques as applied to protein analysis.
• Must possess a solid understanding of protein chemistry and biochemistry, particularly as related to biologics drug development. Experiences with the development of…