Regional Business Director, Auvelity; Chicago, IL

Regional Business Director, Auvelity (Chicago, IL)

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and developing differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry‑leading neuroscience portfolio includes FDA‑approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late‑stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States.

We are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit and follow us on Linked In and X.

Axsome Therapeutics is currently searching for a Regional Business Director (RBD) to lead commercial activities for an assigned geography, establish a team of Account Managers, execute marketing strategies, and ensure a successful launch. The RBD will oversee a highly sophisticated digital infrastructure, supervise sales representatives aligned to geographical boundaries, and drive sales performance at the region level. This cross‑functional front‑line leader role will promote AUVELITY for major depressive disorder in adults and potential future indications.

Field‑based with travel as needed.

• Supervise operations of the region: drive results, hire and coach, develop account managers, manage performance, and assign key priority accounts.
• Develop and implement strategic plans, balancing live/virtual interactions and prioritizing team efforts.
• Plan, organize, and drive performance to achieve the region’s business potential through coaching and influence.
• Establish and maintain effective communication among all region members and cross‑channel stakeholders.
• Maintain technical expertise to respond accurately to product, marketing, policy, and business questions.
• Work with direct reports to understand and execute established expectations.
• Help account managers improve selling skills, product knowledge, and capabilities through coaching and counsel.
• Plan and conduct actions and meetings with region and Market Access teams.
• Manage region business plan, budget, and P&L in alignment with regional and national expectations.
• Ensure compliance with all relevant laws, policies, and processes.
• Travel overnight as required.
• Additional responsibilities as assigned.

• BA or BS required; advanced degree preferred.
• 5+ years of field leadership and/or payer account management experience, or demonstrated sales success with increasing responsibility and organizational leadership.
• Previous pharmaceutical, biotech, or medical marketing/sales experience preferred, with at least 3–5 years in a first‑line leadership position.
• Proven performance history leading others to success through coaching influence.
• Demonstrated ability to deliver outstanding results and develop others to their potential.
• Track record in attracting and retaining top talent.
• Current or recent psychiatry disease experience strongly preferred.
• Successful launch experience strongly preferred.
• Ability to strategize within teams using differential resources to reach business goals.
• Proven ability to run multiple tasks concurrently under aggressive timelines in a dynamic environment.
• Must reside within the territory’s geography.
• Comfortable with uncertainty and high expectations.
• Patient support services experience a plus.
• Strong digital marketing aptitude.
• Strong interpersonal and presentation skills.

The anticipated salary range for this role is $165,000 - $205,000. Axsome offers a competitive employment package that includes an annual bonus, significant equity, and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or…