Senior​/Lead Product Manager, RWE​/Pharma

Fully Remote (US Based)
Chicago , IL 60611
United States

This role requires experience in Pharma and Real World Evidence.

We’re hiring a Senior Product Manager to own strategy and delivery for Genomenon’s Literature-derived Real-World Evidence (RWE) data products and software platforms supporting rare disease and cancer diagnostics and drug development.

You will partner with executive, engineering, scientific, data, and commercial teams to define product direction, translate customer and market needs into clear priorities, and ship solutions that are scientifically credible, commercially valuable, and measurable in impact.

In this role, you will:

• Set and drive product vision, roadmap, and quarterly priorities for our AI-driven real-world evidence products and expert-curated biomedical datasets
• Lead planning and execution across the full product lifecycle (discovery → requirements → build → launch → iteration)
• Align stakeholders and make tradeoffs across scale, speed, scientific rigor, and customer trust
• Guide the work of a small, high-performing AI team and ensure engineering has clear, actionable requirements and success metrics
• Evolve our hybrid model that combines AI and expert curation to meet pharma customer needs

This role is ideal for a strategic, hands‑on product leader with experience in real‑world evidence and advanced AI applications in biomedicine who thrives in a fast‑paced environment and wants to build mission‑driven technology that improves patient outcomes.

• Own strategy and delivery for AI‑extracted real‑world evidence (RWE) products and expert‑curated RWE datasets.
• Lead customer discovery, market research, and competitive analysis to shape roadmap and differentiation.
• Partner with Marketing and Commercial on go‑to‑market plans, messaging, and sales enablement.
• Write and maintain product requirements (PRDs/specs), user stories, and roadmaps; drive sprint‑level execution with Engineering/AI leaders.
• Define clear product positioning, boundaries, and customer expectations across AI insights and curated data.
• Set quality standards for AI outputs (validation, confidence signals, acceptance thresholds) with AI, Science, and Curation leaders.
• Decide where to automate vs require expert review based on use case, regulatory sensitivity, and scientific risk.
• Ensure release readiness, including user acceptance testing for major and minor releases.

• Build and maintain an integrated roadmap that balances innovation, commercial potential, strategic alignment, and scientific rigor.
• Translate emerging AI capabilities into trusted, commercially viable pharma offerings.
• Develop packaging and tiering for different pharma use cases (discovery, translational, clinical, medical affairs).
• Communicate product vision and progress to executives and cross‑functional stakeholders.

• Establish governance and documentation for AI‑driven data products (provenance, assumptions, limitations, review cycles).
• Support customer diligence, audits, and technical deep dives with Scientific and Commercial teams.
• Define and track KPIs (revenue, adoption, delivery) and use them to drive prioritization.
• Improve operating cadence and cross‑functional collaboration across teams.

You are a mission‑driven product professional and strategic, hands‑on leader with a proven ability to earn trust and drive team performance in a fast‑paced environment who thrives at the intersection of science, technology, and business. You know how to guide cross‑functional teams, navigate technical complexity, and translate vision into clear, actionable plans. You bring clarity, energy, and accountability to every stage of the product lifecycle and you’re driven to help shape the future of precision medicine.

You are comfortable operating in ambiguity and guide decisions with data‑driven approaches to ensure alignment with executive decision makers and peers.

• Proven leadership with the ability to earn trust and drive team performance
• Highly organized with strong project and time management skills
• Skilled communicator across executive,…