Postdoctoral Researcher

Overview

Posting Information

Posting Details
Department:
Lineberger Compr Cancer Center - 426801
Posting Open Date: 01/27/2026
Final date to receive applications:
Open Until Filled
Position Type:
Postdoctoral Scholar

Position Title:

Postdoctoral Researcher
Vacancy
Full-time/Part-time:
Full-Time Temporary
Hours per week: 40
FTE: 1

Work Location:

Chapel Hill, NC

Position Location:

North Carolina, US

Qualifications

Hiring Range Dependent on Experience/Qualifications
Proposed Start Date
Estimated Duration of Appointment 12 Months

Position Information

Be a Tar Heel! A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities and is among the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development.

Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country.

UNC
-Chapel Hill offers postdocs comprehensive medical and vision coverage
, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.

Primary Purpose Of Organizational Unit

Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care:
We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education:

We prepare tomorrow's healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.

Research:
We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.

Position Summary

Postdoctoral fellows will conduct research in the areas of Cancer Epigenomics and Single-Cell Technology development and application to advance cancer research. The Xu Lab investigates heterogeneous transcriptional regulation in cancer through three integrated directions: (1) developing cost-effective single-cell multi-modal technologies to track regulatory evolution across tumor progression; (2) defining epigenetic mechanisms that drive diverse cancer and immune cell behaviors and therapeutic responses, using our innovative approaches such as Paired-TF to link regulatory programs with transcriptional outcomes;

and (3) dissecting transcriptional silencer regulation in oncogene sis through large-scale perturbation and single-cell profiling to uncover novel therapeutic targets.

We offer exceptional opportunities for postdocs to take strong leadership and ownership of projects, receive close mentorship, and help shape innovative research directions. Postdoctoral researchers will lead research projects, with specialization in either wet-lab experimentation on multi omics or dry-lab bioinformatic and computational…