Post-Doc Research Associate-Bhatt Lab

Overview

Position Title
:
Post-Doc Research Associate - Bhatt Lab
Dept
:
Gastroint Biology and Dis Ctr - 429001
Posting Open Date
: 09/12/2024
Open Until Filled
:
Yes
Position Type
:
Postdoctoral Scholar
Hours Per Week
: 40
FTE
: 1
Work Location
:
Chapel Hill, NC
Position Location
:
North Carolina, US

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities and is among the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development. The Bhatt Lab at UNC Chapel Hill is seeking motivated scientists with demonstrable bioanalytical expertise to join our team.

Our work advances precision medicine by studying the gut microbiome and its contribution to interindividual variability in drug responses, including efficacy and toxicity. The candidate will have a strong background in bioanalytical techniques and method development using platforms such as LC-MS/MS and HPLC. The central role is developing assays to quantify metabolites of drug metabolism generated by gut microbes and the host using tandem LC-MS/MS.

The candidate will also provide support for method development to the UNC Dept. Of Mass Spectrometry Core laboratory, directed by Dr. Brandie Ehrmann.

The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve, by providing leadership and excellence in patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment and to optimize our partnership with the UNC Health System through close collaboration and commitment to service.

The Bhatt Lab at UNC Chapel Hill seeks motivated scientists with bioanalytical expertise to join our team. The role focuses on studying the gut microbiome to understand drug metabolism and develop strategies to predict and prevent drug-induced injury. The candidate will perform assay development and quantitative mass spectrometry analyses, and contribute to data interpretation and lab collaboration.

PhD in Chemistry, Pharmacology, Analytical Chemistry and/or related field with relevant publications in the field.

• The Research Scientist will design and perform experiments, analyze data, and disseminate findings through manuscripts, grant applications, and presentations. Strong emphasis on quantitative mass spectrometry and handling complex datasets. Experience in mentoring and training undergraduate students.
• Mass spectrometry expertise: hands-on experience with modern MS platforms and software; ability to work with complex datasets.
• Wet lab experience: pipetting, sample extraction, and preparation from biological matrices.
• Data handling: experience with large MS-based datasets.
• Independence and problem solving: ability to work independently and address experimental challenges.
• Communication: clear written and oral communication; experience with manuscripts and grant writing.
• Training & mentorship: ability to train and mentor diverse personnel.
• Flexibility: willingness to work occasional long hours as required.

Required Experience: Prior wet lab experience in pipetting, sample extraction, and sample preparation from biological matrices is preferred.

Experience designing and performing experiments, analyzing data, and disseminating results through manuscripts, grant applications, and oral presentations. Ability to work with undergraduate students. Prior wet lab experience is required. Preferred experience in drug metabolism, intestinal biology/physiology, epithelial biology/physiology, or stem cell biology/physiology. Experience operating mass spectrometry and liquid chromatography instrumentation; quantitative MS using tandem MS is a bonus.

• Must be able to complete repetitive tasks
• May require nights/weekends/after-hours work based on sample/experimental needs
• Must be able to work in a collaborative environment

For information on UNC Postdoctoral Benefits and Services, .