Senior Buyer

Overview

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care. We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit

The Senior Buyer independently leads procurement activities of moderate/large scope and complexity to ensure the organization secures goods and services that meet quality, cost, and delivery objectives. This exempt professional role applies advanced judgment and negotiation skills to supplier management, contract development, and category strategy execution. The Senior Buyer partners cross-functionally to align sourcing decisions with business priorities, contributes to supplier performance improvement, and supports the continuous advancement of procurement practices across the organization.

This role is based at our Durham, North Carolina, office and offers a flexible working arrangement. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.

• Partner with key function(s) within the organization
• Lead sourcing and procurement for materials, equipment, and services, applying strategic and analytical judgment to achieve optimal cost, quality, and delivery outcomes.
• Manage day-to-day Source-to-Pay processing in GRAIL’s ERP systems, including processing purchase requisitions, oversight to invoices as needed, and new supplier creation
• Develop and execute supplier negotiations, contracts, and pricing agreements that align with business and compliance requirements, including modeling out complex cost models and savings
• Partner with internal stakeholders to define specifications, demand forecasts, and project requirements supporting operational and strategic goals
• Manage supplier relationships to ensure performance, quality, and service levels are met while identifying opportunities for improvement and innovation
• Resolve escalated supplier and contractual issues using sound professional discretion and business acumen
• Contribute to the development of category strategies, sourcing frameworks, and process improvements that enhance procurement efficiency and value delivery
• Prepare procurement analyses, spend reports, and performance summaries to support data-driven decision-making
• Provide guidance and mentorship to less experienced buyers to strengthen team capability and consistency of execution
• Ensure all procurement activities adhere to corporate policies, ethical standards, and applicable regulatory requirements
• Note:
  
  These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion

• Bachelor’s degree in Supply Chain, Business Administration, Finance, or related field
• 5+ years of relevant procurement, sourcing, or supply chain experience; or Master’s degree with 2+ years of experience
• Demonstrated experience leading negotiations and managing supplier relationships
• Proficiency in ERP / Source-to-Pay systems, procurement tools, and contract management processes

• Attention to detail; organized with ability to manage multiple activities simultaneously
• Excellent written…