Postdoctoral Project Research Scientist - F Rouhani Lab

About the Role

We are looking for an enthusiastic and ambitious Postdoctoral Project Research Scientist to join the Rouhani Lab. The lab is dedicated to understanding the factors underlying an organ's regenerative capacity in order to design novel therapeutics to augment biological function. Our long‑term vision is to apply our findings to stimulate regeneration in other non‑proliferative tissues, understand the process of organ ageing, and elucidate the molecular steps to cancer.

As a PPRS you will drive a project in collaboration with AstraZeneca to develop next‑generation in vitro and ex vivo models of liver biology. The role involves working with bioengineers at the Francis Crick Institute to develop a novel microfluidic perfusion‑based system that keeps patient‑derived liver tissue viable and functional in the lab for prolonged periods under physiological conditions.

• Adapt existing technologies and build next‑generation microfluidic device prototypes under guidance from the Making Labs.
• Test the viability and function of liver tissues.
• Apply gene editing to modulate cellular function.
• Acquire, analyse and review scientific data.
• Work independently to drive the project to completion in a timely manner.
• Collaborate with other lab members and scientists across the Crick.
• Contribute to the Crick’s culture of innovation, openness, and collegiality.

• PhD awarded or in the final stages of PhD submission in related fields.
• Strong track record of writing papers, evidenced by publications in high‑impact journals.
• Expertise in bioinformatics, human genomics, or analysis of high‑throughput data.
• Deep knowledge and experience within core laboratory skills, such as molecular biology.
• Ability to clearly document work and communicate results effectively.
• Ability to work independently and meet key deadlines.

This is a full‑time, fixed‑term 2‑year position on Crick terms and conditions of employment. Applicants for this role will be eligible for sponsorship to work in the UK.

• Visas: sponsorship to work in the UK.
• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
• Pension Scheme:
  Defined contribution pension with employer contributions of up to 16%.
• Health & Well‑being: 24/7 GP consultation services, occupational health services and mental health support programmes, eye care vouchers and discounted healthcare plans.
• Work‑Life Balance:
  Back‑up care for dependents, childcare support allowance, annual leave purchase options.
• Crick Networks: community and inclusive social events.
• Perks: discounted gym memberships, bike‑to‑work scheme, shopping discounts, subsidised on‑site restaurant and social spaces.
• Career support:
  Post‑doc to PI programme and other career development activities.

We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. We are a Disability Confident employer and will make reasonable adjustments if you need them.

Please email:

Europe’s largest biomedical research institute, the Crick combines world‑class scientists and staff to collaborate on vital research that helps prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick supports a dynamic environment that fosters excellence with state‑of‑the‑art infrastructure and a creative, curious culture. We cut across traditional boundaries to pursue bold ideas, support each researcher’s freedom, and aim to translate our science into benefits for human health and the economy.