Global Medical Director, Breast Cancer​/Pan-Tumor

Overview

If you are a current Jazz employee please apply via the Internal Career site.

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases - often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments.

Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit  for more information.

The Breast Cancer / Pan Tumor Medical Director (MD) will, in partnership with the Global Medical Affairs Lead, co lead the development and execution of strategic medical plans for this molecule across breast cancer and broader pan tumor indications. The role will drive the implementation of global and regional medical affairs activities aligned with the overarching strategy. Deep medical affairs expertise and strong clinical knowledge in oncology are essential, with a preference for experience in breast cancer, HER2 expressing tumors, or targeted therapies.

As a key member of the Global Medical and Scientific Affairs (GMSA) organization, the MD will report directly to the Therapy Area Head, Oncology. The successful candidate will co create and lead annual and long range Global Medical Plans, including integrated evidence generation strategies, ensuring alignment with Franchise and Global Product Team (GPT) objectives. This individual will demonstrate leadership within a fast paced, high performing medical team, foster cross functional collaboration, and communicate effectively across global and regional stakeholders.

The role requires strong partnerships with Medical Affairs, Clinical Development, Commercial, Regulatory, and Market Access teams, as well as influential engagement with external experts in breast cancer and other relevant tumour types.

• Colead the development and execution of annual and longrange Global Medical Plans and evidence generation strategies for the assigned molecule in breast cancer and pantumour settings.
• Drive global and regional medical affairs strategies, ensuring actionable insights inform robust, cross functional plans.
• Actively influence the Medical Functional Matrix Team (FMT) for the molecule and lead team meetings when delegated.
• In collaboration with the GMAL, oversee protocol and study design development, ensuring scientific rigor and strategic alignment across tumour types.
• Build impactful scientific platforms and narratives that shape diseasearea and product positioning in breast cancer and broader HER2expressing malignancies.
• Codirect global medical communications strategy and publication planning, ensuring timely, high quality scientific deliverables.
• Provide strategic guidance for core materials (e.g., training decks, scientific platforms, study summaries) for global and regional dissemination.
• Partner with Commercial to colead launch readiness and lifecycle management initiatives across multiple tumour indications.
• Represent Global Medical Affairs at cross functional team meetings and external scientific or medical engagements.
• Maintain deep subject matter expertise in breast cancer and pantumour HER2 biology, anticipating diseasearea evolution through competitive intelligence and insights generation.
• Build and maintain external stakeholder engagement plans, including expert mapping, advisory boards, and collaborative opportunities with key opinion leaders.
• Champion patient advocacy initiatives in partnership with Global Advocacy teams, ensuring patient perspectives inform strategy.
• Contribute to the Investigator Sponsored Trial (IST) and collaborative research strategy across tumour types.

• Strong background in solid tumours, preferably breast cancer and/or HER2targeted therapies.
• Minimum of 5 years  experience in Medical Affairs with demonstrated leadership in strategic planning and execution.
• Proven ability to shape medical strategies that drive clinical impact and business success.
• Experience leading Phase IV studies, ISTs, and Real World Evidence initiatives.
• Expertise across marketed and pipeline products with strong strategic and operational leadership capabilities.
• Ability to influence and operate effectively within complex matrix environments.
• Strong understanding of regulatory, commercialization, market access, and reimbursement frameworks.
• Exceptional communication skills and leadership presence in high growth, fastpaced settings.
• Willingness to travel as required.

• Doctoral degree required…