Scientific Senior Director, ADCs Discovery Biology, Oncology

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome.

We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.

We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Our Bristol Myers Squibb research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.

We are seeking a highly accomplished and creative scientific leader to lead the BMS Oncology ADC Discovery team and oversee the preclinical ADC portfolio. In this role, you will shape the overall Oncology ADC strategy by providing scientific and strategic insight and influencing key investment decisions. You will lead a growing internal ADC discovery portfolio and cultivate external partnerships to drive innovation—all with the goal of advancing next generation ADCs into the clinic.

Our team thrives on collaboration, creativity, rigorous science and a shared commitment to transforming cancer care.

• Lead the BMS Oncology ADC strategy and portfolio, guiding programs from target concept through development candidate and into the clinic.
• Partner closely with key internal stakeholders—including leaders in Research, Development, and Commercial—to ensure alignment and effective execution.
• Build and maintain external collaborations that strengthen and differentiate the ADC portfolio.
• Serve as a credible and influential spokesperson and subject matter expert for ADC discovery, shaping both internal and external investment decisions.
• Work across the organization to align strategy and ensure timely advancement of innovative ADC programs into clinical development.
• Make informed decisions that enable the ADC team to deliver on its objectives and meet stakeholder expectations.
• Foster a culture of integrity, accountability, and responsible innovation.
• Communicate effectively and engage collaboratively using strong interpersonal and communication skills.

• Bachelor's Degree
• 15+ years of academic / industry experience
• Master's Degree
• 12+ years of academic / industry experience
• PhD
• 10+ years of academic / industry experience
• 8+ years of leadership experience

• Ph.D. or equivalent advanced degree in the Life Sciences
• 10+ years of industry experience
• 8+ years of industry leadership experience
• Extensive experience in ADC discovery, with a deep understanding of ADC technologies spanning both cytotoxic and novel payload classes along with expertise in conjugation and linker strategies.
• Experience developing and managing an ADC portfolio that spans early target discovery through delivery of clinical candidates.
• Extensive experience building and leading high performing, highly collaborative teams dedicated to advancing innovative ADCs into clinical development.
• Excellent strategic thinking skills, consistently weighing risk, benefit, and tradeoffs to guide sound decision making.
• Excellent communication skills, with the ability to clearly articulate complex…