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Head of Translational Immunology

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Biogen, Inc.
Full Time position
Listed on 2026-03-10
Job specializations:
  • Research/Development
  • IT/Tech
    Data Science Manager
Salary/Wage Range or Industry Benchmark: 125000 - 150000 USD Yearly USD 125000.00 150000.00 YEAR
Job Description & How to Apply Below
** About This Role
** As the Head of Translational Immunology, you will play a critical leadership role in driving innovation and advancing the organization’s research and development initiatives. You will join a dynamic team dedicated to the discovery, development, implementation, and interpretation of translational and clinical biomarker strategies to support the Immunology portfolio.

Key responsibilities include leading the design, execution, and integration of biomarker strategies from early Research through early clinical development. A central focus of this role is advancing innovative translational approaches that integrate diverse human datasets—including genomics, transcriptomics, proteomics, cellular models, and clinical data—to inform novel therapeutic targets, generate actionable hypotheses, and provide supporting evidence for programs across the Immunology pipeline.
** What You’ll Do
**** Strategic Leadership and Team Building
*** Lead and mentor a high-performing team of research and clinical stage biomarkers scientists
* Formulate and implement a strategic vision for Translational Immunology to drive the development of innovative clinical biomarkers across our Immunology portfolio, supporting future research targets, indication expansion, and mechanism of action (MOA) insights.
* Matrix-manage biomarker and systems biology scientists across various sub-functions to collaboratively develop and implement integrated biomarker strategies, while fostering a culture of innovation, collaboration, and scientific excellence within the Biomarkers and Systems Biology function and across the Research organization.
** Human-Centric Data Generation and Integration
*** Provide strategic, technical, and scientific leadership in designing, validating, implementing, and interpreting data from an integrated clinical biomarker plan to support first-in-human studies, decision-making, and proof-of-biology studies for clinical programs.
* Emphasize human-focused approaches, leading efforts to prioritize the use of human model systems, including human pathology samples and human clinical trial data, to ensure translational relevance and directly inform therapeutic development, using human data as the foundation for uncovering disease mechanisms and identifying therapeutic opportunities.
* Partner with the computational biology team to harness the integration of human omics datasets (e.g., genomics, transcriptomics, proteomics, metabolomics) as tools to identify novel translational insights into disease mechanisms and therapeutic opportunities from internal and external sources
** External Partnerships and Collaboration
*** Maintain scientific excellence in immunology-relevant biomarkers, assay development and validation, patient characterization, and relevant diagnostics
* Identify and establish partnerships with academic institutions, specialty startups, CROs, and industry consortia to enhance internal capabilities and expedite the achievement of biomarker objectives
* Leverage external expertise and resources, including the latest advancements in translational Immunology approaches, to complement internal research efforts
** Interdisciplinary Collaboration and Innovation
*** Work closely with cross-functional teams, including other biomarker and systems biology colleagues, biologists, chemists, clinicians, and development colleagues, to integrate a comprehensive Immunology Biomarker approach
* Promote seamless collaboration between team members and biomarker analytical scientists to drive data-driven decision-making
* Lead cross-functional initiatives aimed at developing and applying novel Immunology approaches, focusing on biological networks and disease processes to enable clinical decisions
** Who You Are
** You are an accomplished leader with a passion for Immunology and a proven track record of leveraging translational and biomarker strategies to drive innovation in drug discovery and clinical development. You bring deep expertise in translational immunology, biomarker science, and data integration, combined with exceptional leadership and collaboration skills. You excel at translating complex scientific data…
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