Research Associate - Molecular Biology

Job Title:
Contract Scientist – Protein Optimization (Laboratory Support)

Location: Cambridge, MA

Assignment Type: Contract (1 year)

Schedule: Full-Time

A leading global biopharmaceutical organization is seeking a Contract Scientist to support its Protein Optimization team in Cambridge, MA. This laboratory-based role will focus on accelerating yeast display and molecular biology workflows through hands‑on experimental support.

The ideal candidate will bring strong bench‑level molecular biology experience and the ability to reliably execute established protocols while maintaining detailed documentation. This position is well‑suited for a Research Associate to Associate Scientist‑level professional who thrives in a collaborative, fast‑paced research environment.

• Perform routine, hands‑on molecular biology workflows to support protein optimization and yeast display efforts
• Execute yeast transformations, colony picking, routine cell maintenance, and culturing
• Conduct plasmid preparation, PCR amplification, gel electrophoresis, and DNA purification
• Prepare DNA samples suitable for next‑generation sequencing (NGS)
• Support cloning efforts including restriction digest, gel purification, combinatorial library design, and saturation mutagenesis
• Assist with DNA insert design and coordinate external synthesis as needed
• Operate flow cytometry analyzers and FACS sorters to support yeast display workflows
• Prepare yeast cultures for FACS sorting and extract DNA from selected populations
• Register DNA and protein sequences in internal systems for proper documentation and banking
• Maintain meticulous laboratory records and collaborate closely with cross‑functional scientific teams

Education:

• B.S. in Molecular Biology, Biochemistry, Biophysics, Immunology, or a related field

Experience:

• At least 1 year of hands‑on laboratory experience
• Strong molecular biology skills including cloning, transformation, plasmid prep, PCR, and sequence analysis
• Experience with sterile technique and cell culture
• Working knowledge of protein engineering methods
• Demonstrated ability to work effectively within a collaborative research team
• Strong written and verbal communication skills
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Preferred Qualifications
• Industry experience in biotechnology or pharmaceutical settings
• Experience with yeast, mammalian, or phage display systems
• Hands‑on experience preparing and handling samples for next‑generation sequencing
• Experience operating flow cytometry analyzers and FACS sorters
• Basic understanding of antibody structure and function
Additional Information
• Proficiency in written and spoken English required
• Some travel may be required

Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce.

Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E‑Verify and will provide the federal government with your Form I‑9 information to confirm that you are authorized to work in the U.S.