Technical Associate , Yaffe Lab

MIT - Koch Institute for Integrative Cancer Research

Recruitment began on December 22, 2025

and the job listing Expires on February 22, 2026

TECHNICAL ASSOCIATE I, YAFFE LAB, Koch Institute for Integrated Cancer Research - Yaffe Lab, to work closely with several lab members and perform independent research using CRISPR-based screens for sensitization of tumor cells to signaling pathway inhibitors and chemotherapeutic drugs, combined with in vivo mouse tumor studies.

• Perform a broad range of basic laboratory experiments using standard techniques, including tissue culture techniques, CRISPR screening, maintaining mouse tumor and human PDX models, delivery of novel anti-cancer therapeutics into mice and target tumors, molecular cloning, immunoblotting, flow cytometry, and other biochemical/molecular assays
• Statistical data analysis; evaluating, designing, and revising research methods/procedures/techniques based on established objectives; and adjusting basic experimental protocols to ensure project completion in a timely fashion

• REQUIRED:
  
  Bachelor’s degree in a relevant field; two years of specialized lab experience (may include experience gained as an undergraduate); working knowledge of general laboratory practices and procedures; experience with mouse cancer models, signal transduction biochemistry, and relevant molecular biology and cell culture techniques; experience conducting and applying online research to projects; excellent communication and interpersonal skills; comfort analyzing, summarizing, and reporting results to researchers;
  
  commitment to exceeding quality standards, providing exceptional services, and producing accurate and high-quality work; meticulous attention to detail; and ability to follow safety procedures, maintain a safe work environment, and work independently and as part of a team

• MASTER’s degree in related field; broad knowledge of the work done in the labs; and experience collaborating with a diverse group of researchers/trainees

Exerting light-to-medium amount of force to move objects of 10-20lbs; moving long distances or from site to site; proximity to mechanical parts and electrical current; and exposure to high heat or chemicals.